Gilberto Fisone received his training in biology at the University of Pavia (Italy) and his PhD at the University of Stockholm (Sweden). In 1990, Dr. Fisone joined the laboratory of Dr. Paul Greengard at the Rockefeller University (New York), where he later joined the faculty as an assistant professor. Since then, he has been studying the molecular mechanisms underlying neurotransmission in the basal ganglia. In 1995, he took a job as an assistant professor in the department of neuroscience at the Karolinska Institutet, Stockholm, where he began to investigate the involuntary movements, or dyskinesias, produced by long-term treatment with L-DOPA. His work has elucidated several abnormalities implicated in this condition, including changes in key neuronal signaling pathways. Recently, his work has focused on modeling and characterizing the non-motor symptoms of Parkinson’s disease. He is currently professor and chair of the department of neuroscience at Karolinska Institutet.