Jing Zhang, MD, PhD, a board-certified anatomical and neuropathologist, has been deeply involved in proteomics-based discovery work, as well as targeted validation of candidate proteins related to neurodegenerative disorders including Parkinson's disease (PD) and Alzheimer's disease (AD). As one of the leaders in the PD biomarker field, Dr. Zhang has used both mass spectrometry (MS) and immunoassay techniques on numerous platforms (xMAP Luminex, MSD and ELISA) to discover and then develop assays (SRM, immunoassays, including de novo ones) for protein/peptide biomarkers in several different biospecimens (brain tissue, CSF, blood plasma and saliva). Most of these studies have been conducted in collaboration with multiple medical centers located both domestically and internationally. In addition, Dr. Zhang’s group has worked with several large cohorts on biomarker research, including those collected by various Udall centers, DATATOP and the ADNI, with many papers published. The group has also worked with the PPMI extensively on several projects in the past.
Associated Grants
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Using Human Cerebrospinal Fluid Samples Collected in DATATOP Study for Biomarker Validation in Patients with Parkinson disease
2011
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Isoforms of Alpha-synuclein as Biomarkers for Diagnosis and Progression of Parkinson's Disease
2007
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