Professor Maria Paula Macedo graduated from the University of Lisbon with a degree in pharmacy and received her PhD from the University of Manitoba, Canada. Following a one-year postdoctoral fellowship at the Institute Gulbenkian of Science (Portugal) she was appointed professor of pharmacology at the Institute of Health Sciences (Portugal). She is currently a professor at NOVA Medical School, where she heads the MEDIR research and implements and co-coordinates the APDP-EducationResearchCenter (APDP-Diabetes-Portugal). Professor Macedo has been devoted to studying diabetes and its comorbidities, from molecular mechanisms to clinical implications. Her research focuses on meal-induced insulin sensitization in prediabetes and diabetes comorbidities, autonomic nervous system regulation of glucose and lipid metabolism, the genetic and environmental factors controlling insulin clearance and resistance, the effects of inflammation on hepatic insulin clearance and dysmetabolism, and the intertwining of metabolic dysregulation and the central nervous system, particularly in Parkinson’s disease.
Associated Grants
-
Evaluating an Insulin-degrading Enzyme as a Novel Therapeutic Target for Parkinson’s Disease
2022