Pier G. Mastroberardino is a principal investigator at the FIRC Institute for Molecular Oncology, in Milan, Italy, and at the Erasmus Medical Center in Rotterdam, the Netherlands. His research groups investigate the molecular pathogenesis of Parkinson’s disease (PD) from the perspective of mitochondrial dysfunction, iron metabolism and redox homeostasis. The labs also have a strong interest in the processes associated with aging that might synergize with genetic and environmental factors to trigger PD pathogenesis. In this context, Dr. Mastroberardino and his colleagues are actively engaged in studying DNA damage and repair, given their proven role in aging. The laboratories take advantage of multiple biological systems including cell cultures, zebrafish, toxicological and genetic mammalian models and stem cell-derived neurons to gather knowledge that can be used to understand PD in people.