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Rajeshwar Awatramani, PhD

Professor at Northwestern University

Location: Chicago, IL United States

Rajeshwar Awatramani, PhD, is a Professor of Neurology at the Northwestern University Feinberg School of Medicine. He received his PhD from the University of Pennsylvania and completed his postdoctoral training at Harvard University. The focus of his research has been the development and diversity of dopamine (DA) neurons. His lab has described the floor plate origin of DA neurons and is continuing to explore how floor plate progenitors are subdivided to give rise to the diverse adult midbrain DA neuron system.

His lab also focuses on understanding DA neuron diversity. Using single cell profiling, his lab revealed the presence of putative DA neuron subtypes. To decipher the functional basis of DA neuron heterogeneity, Dr. Awatramani has developed a powerful set of intersectional genetic tools to access DA neuron subtypes and has found anatomical and functional heterogeneity even within a single anatomical cluster like the substantia nigra. 


Associated Grants

  • Redefining Parkinson’s Disease Pathophysiology Mechanisms in the Context of Heterogeneous Substantia Nigra Neuron Subtypes

    2021


  • Genetic Dissection of Parkinson's Disease Vulnerable Dopaminergic Neurons Population

    2010


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