Dr. Sheng Luo is professor of biostatistics and bioinformatics at Duke University and received his PhD in biostatistics from The Johns Hopkins University. Dr. Luo is a leading expert in designing and applying novel statistical methods in the design and analysis of clinical trials data and neurodegenerative disorders. He has more than 160 peer-reviewed articles published in high-impact journals and has served as principle investigator (PI) and MPI for numerous NIH grants on statistical methodology development. Dr. Luo is co-PI of Data Management and Statistics Core in the newly funded Duke/UNC Alzheimer’s Disease Research Center (ADRC). He is also PI of multiple projects regarding novel latent variable modeling and various neurodegenerative disorders rating scale development, validation and translation funded by Parkinson’s Foundation, CHDI Foundation and Movement Disorders Society. Dr. Luo has served as the primary faculty statistician in numerous clinical trials and multiple Data and Safety Monitoring Boards.