At the end of her medical studies at Homburg Saar University in 1995, Dr. Behnke started to work with transcranial ultrasound involving the detection of microemboli using transcranial Doppler sonography. During her training as a neurologist at the department of neurology of the University Hospital Homburg Saar, she worked with department director Prof. Georg Becker, who was the first to investigate the brains of patients with neurodegenerative disorders with transcranial sonography (TCS). During this time, she learned the technique of imaging the brain parenchyma by TCS and began working with Prof. Daniela Berg who, together with Prof. Becker, established TCS as a valuable tool in the diagnosis of Parkinson’s disease (PD) and other movement disorders. In the following years Dr. Behnke continued to work on TCS changes in patients with neurodegenerative diseases, especially PD, atypical Parkinsonian syndromes and dystonia, and in healthy controls. In 2003, she spent two months supported by the German Research Society (DFG) at the Prince of Wales Medical Research Institute in Sydney, Australia, assessing TCS changes in normal ageing. Dr. Behnke is currently in charge of neurological in-patients care at the University Hospital Homburg Saar, Germany. Moreover, she is head of the ultrasound department and of the outpatients clinic for dystonia. Her current major scientific interest is the value of TCS as a diagnostic tool in early or yet subclinical PD and as a vulnerability marker for PD.