Vesna Sossi, PhD, is a professor in the Physics Department at the University of British Columbia (UBC) in Canada, the director of the UBC Positron Emission Tomography (PET) Imaging Laboratory and closely associated with the Pacific Parkinson’s Research Center. She is an expert in PET imaging applied to the study of Parkinson’s disease (PD), investigating its origin and treatment-related complications. Her laboratory pioneered novel image analysis methods as applied to PET to be used in this proposal and she holds several Michael J. Fox Foundation and other grants to investigate the LRRK2-associated mechanisms leading to an increased risk of PD, both in humans and pre-clinical models.