5651 - 5700 of 5857 Results
Title
Year
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OPENTitle: Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic miceJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 40Issue #: 3Start Page: 503End Page: 517Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2010.07.010Best OA location URL: https://europepmc.org/articles/pmc2955774?pdf=renderCitation Count: 264
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OPENTitle: Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localizationJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 430Issue #: 3Start Page: 405End Page: 413Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bj20100784Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/405/664434/bj4300405.pdfCitation Count: 373
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OPENTitle: 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localizationJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 430Issue #: 3Start Page: 393End Page: 404Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1042/bj20100483Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/393/878058/bj4300393.pdfCitation Count: 383
- Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease2010OPENTitle: Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson diseaseJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 120Issue #: 8Start Page: 2745End Page: 2754Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci42642Best OA location URL: http://www.jci.org/articles/view/42642/files/pdfCitation Count: 397
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OPENTitle: Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective N-Methyl-d-aspartate Receptor AntagonistsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 53Issue #: 15Start Page: 5476End Page: 5490Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm100027pBest OA location URL: https://europepmc.org/articles/pmc2920070?pdf=renderCitation Count: 84
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OPENTitle: Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutationsJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 33Issue #: 4Start Page: 814End Page: 823Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2010.05.009Best OA location URL: https://doi.org/10.1016/j.neurobiolaging.2010.05.009Citation Count: 211
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OPENTitle: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 20Issue #: 17Start Page: 5175End Page: 5178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007Best OA location URL: https://europepmc.org/articles/pmc2922490?pdf=renderCitation Count: 29
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OPENTitle: Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementiaJournal Name: Experimental NeurologyPublisher: Elsevier BVVol: 225Issue #: 1Start Page: 210End Page: 218Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.06.017Best OA location URL: https://europepmc.org/articles/pmc2922478?pdf=renderCitation Count: 182
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OPENTitle: Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 VectorsJournal Name: Molecular TherapyPublisher: Elsevier BVVol: 18Issue #: 8Start Page: 1490End Page: 1495Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/mt.2010.114Best OA location URL: http://www.cell.com/article/S1525001616310991/pdfCitation Count: 79
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OPENTitle: Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's diseaseJournal Name: Neuroscience LettersPublisher: Elsevier BVVol: 480Issue #: 1Start Page: 78End Page: 82Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neulet.2010.06.009Best OA location URL: https://europepmc.org/articles/pmc2943649?pdf=renderCitation Count: 196
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OPENTitle: Standard guidelines for publication of deep brain stimulation studies in Parkinson's disease (Guide4DBS‐PD)Journal Name: Movement DisordersPublisher: WileyVol: 25Issue #: 11Start Page: 1530End Page: 1537Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.23151Best OA location URL: https://europepmc.org/articles/pmc4775095?pdf=renderCitation Count: 25
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OPENTitle: Low‐dose bafilomycin attenuates neuronal cell death associated with autophagy‐lysosome pathway dysfunctionJournal Name: Journal of NeurochemistryPublisher: WileyVol: 114Issue #: 4Start Page: 1193End Page: 1204Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2010.06838.xBest OA location URL: https://europepmc.org/articles/pmc2910188?pdf=renderCitation Count: 74
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OPENTitle: Dystrophin-associated protein scaffolding in brain requires α-dystrobrevinJournal Name: NeuroReportPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 21Issue #: 10Start Page: 695End Page: 699Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/wnr.0b013e32833b0a3bBest OA location URL: https://europepmc.org/articles/pmc2889226?pdf=renderCitation Count: 14
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OPENTitle: Risk of sleep-disordered breathing in Parkinson's diseaseJournal Name: Sleep and BreathingPublisher: Springer Science and Business Media LLCVol: 15Issue #: 3Start Page: 471End Page: 478Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s11325-010-0362-3Best OA location URL: https://europepmc.org/articles/pmc2978748?pdf=renderCitation Count: 43
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OPENTitle: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged miceJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 107Issue #: 21Start Page: 9879End Page: 9884Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1004676107Best OA location URL: https://europepmc.org/articles/pmc2906862?pdf=renderCitation Count: 484
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OPENTitle: Lentiviral Overexpression of GRK6 Alleviates l -Dopa–Induced Dyskinesia in Experimental Parkinson’s DiseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 2Issue #: 28Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.3000664Best OA location URL: https://europepmc.org/articles/pmc2933751?pdf=renderCitation Count: 135
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OPENTitle: LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's diseaseJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 40Issue #: 1Start Page: 73End Page: 81Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2010.04.002Best OA location URL: https://europepmc.org/articles/pmc2926296?pdf=renderCitation Count: 138
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OPENTitle: Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasmJournal Name: Protein Engineering, Design and SelectionPublisher: Oxford University Press (OUP)Vol: 23Issue #: 6Start Page: 489End Page: 498Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/protein/gzq022Best OA location URL: https://academic.oup.com/peds/article-pdf/23/6/489/17494272/gzq022.pdfCitation Count: 58
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OPENTitle: Effects of aging on the ventral and dorsal substantia nigra using diffusion tensor imagingJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 33Issue #: 1Start Page: 35End Page: 42Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2010.02.006Best OA location URL: https://europepmc.org/articles/pmc2908724?pdf=renderCitation Count: 55
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OPENTitle: Patient-specific analysis of the relationship between the volume of tissue activated during DBS and verbal fluencyJournal Name: NeuroImagePublisher: Elsevier BVVol: 54Issue #:Start Page: S238End Page: S246Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuroimage.2010.03.068Best OA location URL: https://europepmc.org/articles/pmc2908727?pdf=renderCitation Count: 107
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OPENTitle: Parkinson’s PsychosisJournal Name: Current Treatment Options in NeurologyPublisher: Springer Science and Business Media LLCVol: 12Issue #: 3Start Page: 200End Page: 211Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s11940-010-0072-yBest OA location URL: https://europepmc.org/articles/pmc3045857?pdf=renderCitation Count: 25
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OPENTitle: Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disordersJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 119Issue #: 6Start Page: 689End Page: 702Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-010-0664-3Best OA location URL: https://europepmc.org/articles/pmc2866090?pdf=renderCitation Count: 795
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OPENTitle: High regulatability favors genetic selection in SLC18A2 , a vesicular monoamine transporter essential for lifeJournal Name: The FASEB JournalPublisher: WileyVol: 24Issue #: 7Start Page: 2191End Page: 2200Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1096/fj.09-140368Best OA location URL: https://europepmc.org/articles/pmc2887259Citation Count: 16
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OPENTitle: Incidental Lewy body disease: Clinical comparison to a control cohortJournal Name: Movement DisordersPublisher: WileyVol: 25Issue #: 5Start Page: 642End Page: 646Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.22971Best OA location URL: https://europepmc.org/articles/pmc2935627?pdf=renderCitation Count: 131
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions2010OPENTitle: Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusionsJournal Name: Nature GeneticsPublisher: Springer Science and Business Media LLCVol: 42Issue #: 3Start Page: 234End Page: 239Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ng.536Best OA location URL: https://europepmc.org/articles/pmc2828525?pdf=renderCitation Count: 544
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OPENTitle: Impact of belief in neuroprotection on therapeutic intervention in Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 25Issue #: 8Start Page: 1082End Page: 1086Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.22997Best OA location URL: https://europepmc.org/articles/pmc2891220?pdf=renderCitation Count: 1
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OPENTitle: Impact of dendritic spine preservation in medium spiny neurons on dopamine graft efficacy and the expression of dyskinesias in parkinsonian ratsJournal Name: European Journal of NeurosciencePublisher: WileyVol: 31Issue #: 3Start Page: 478End Page: 490Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1460-9568.2010.07077.xBest OA location URL: https://europepmc.org/articles/pmc2940228?pdf=renderCitation Count: 63
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OPENTitle: Mutational analysis of parkin and PINK1 in multiple system atrophyJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 32Issue #: 3Start Page: 548.e5End Page: 548.e7Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2009.11.020Best OA location URL: https://europepmc.org/articles/pmc3934211?pdf=renderCitation Count: 21
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OPENTitle: The relationship between uric acid levels and Huntington's disease progressionJournal Name: Movement DisordersPublisher: WileyVol: 25Issue #: 2Start Page: 224End Page: 228Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.22907Best OA location URL: https://europepmc.org/articles/pmc2831113?pdf=renderCitation Count: 90
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OPENTitle: MKK6 binds and regulates expression of Parkinson’s disease‐related protein LRRK2Journal Name: Journal of NeurochemistryPublisher: WileyVol: 112Issue #: 6Start Page: 1593End Page: 1604Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2010.06568.xBest OA location URL: https://europepmc.org/articles/pmc2856721?pdf=renderCitation Count: 100
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OPENTitle: A Tangled Web – Tau and Sporadic Parkinson's DiseaseJournal Name: Frontiers in PsychiatryPublisher: Frontiers Media SAVol: 1Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fpsyt.2010.00150Best OA location URL: https://www.frontiersin.org/articles/10.3389/fpsyt.2010.00150/pdfCitation Count: 32
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OPENTitle: Biopsable Neural Tissues: Toward New Biomarkers for Parkinson's Disease?Journal Name: Frontiers in PsychiatryPublisher: Frontiers Media SAVol: 1Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fpsyt.2010.00128Best OA location URL: https://www.frontiersin.org/articles/10.3389/fpsyt.2010.00128/pdfCitation Count: 40
- Evaluation of the Braak staging scheme for Parkinson's disease: Introduction to a panel presentation2010OPENTitle: Evaluation of the Braak staging scheme for Parkinson's disease: Introduction to a panel presentationJournal Name: Movement DisordersPublisher: WileyVol: 25Issue #: S1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.22783Best OA location URL: https://europepmc.org/articles/pmc2929458?pdf=renderCitation Count: 20
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OPENTitle: Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after EndocytosisJournal Name: NeuronPublisher: Elsevier BVVol: 65Issue #: 1Start Page: 66End Page: 79Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.neuron.2009.12.023Best OA location URL: http://www.cell.com/article/S0896627309010411/pdfCitation Count: 942
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OPENTitle: LRRK2 and the Stress Response: Interaction with MKKs and JNK-Interacting ProteinsJournal Name: Neurodegenerative DiseasesPublisher: S. Karger AGVol: 7Issue #: 1-3Start Page: 68End Page: 75Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1159/000285509Best OA location URL: https://karger.com/ndd/article-pdf/7/1-3/68/3138541/000285509.pdfCitation Count: 59
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OPENTitle: Maladaptive striatal plasticity in l-DOPA-induced dyskinesiaJournal Name: Progress in Brain ResearchPublisher: ElsevierVol:Issue #:Start Page: 209End Page: 233Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/s0079-6123(10)83011-0Best OA location URL: https://europepmc.org/articles/pmc2930606?pdf=renderCitation Count: 196
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OPENTitle: Mitochondrial therapies for Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 25Issue #: S1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.22781Best OA location URL: https://europepmc.org/articles/pmc5797696?pdf=renderCitation Count: 57
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OPENTitle: Therapeutic directions for Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 25Issue #: S1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.22790Best OA location URL: https://europepmc.org/articles/pmc3110693?pdf=renderCitation Count: 7
- α-Synuclein Gene May Interact with Environmental Factors in Increasing Risk of Parkinson’s Disease2010OPENTitle: α-Synuclein Gene May Interact with Environmental Factors in Increasing Risk of Parkinson’s DiseaseJournal Name: NeuroepidemiologyPublisher: S. Karger AGVol: 35Issue #: 3Start Page: 191End Page: 195Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1159/000315157Best OA location URL: https://europepmc.org/articles/pmc2945263?pdf=renderCitation Count: 61
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OPENTitle: Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease modelsJournal Name: Disease Models & MechanismsPublisher: The Company of BiologistsVol: 3Issue #: 3-4Start Page: 194End Page: 208Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1242/dmm.004267Best OA location URL: https://dspace.mit.edu/bitstream/1721.1/66913/1/SuetalDMM09.pdfCitation Count: 177
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OPENTitle: Sensitivity and specificity of the finger tapping task for the detection of psychogenic movement disordersJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 16Issue #: 3Start Page: 197End Page: 201Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2009.11.007Best OA location URL: https://europepmc.org/articles/pmc2829355?pdf=renderCitation Count: 30
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OPENTitle: Comparative Transduction Efficiency of AAV Vector Serotypes 1–6 in the Substantia Nigra and Striatum of the Primate BrainJournal Name: Molecular TherapyPublisher: Elsevier BVVol: 18Issue #: 3Start Page: 588End Page: 593Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/mt.2009.286Best OA location URL: http://www.cell.com/article/S1525001616323085/pdfCitation Count: 124
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OPENTitle: Are there differences in cerebral white matter lesion burdens between Parkinson’s disease patients with or without dementia?Journal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 119Issue #: 1Start Page: 147End Page: 149Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-009-0620-2Best OA location URL: https://europepmc.org/articles/pmc2928051?pdf=renderCitation Count: 45
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OPENTitle: Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s DiseaseJournal Name: Neurotoxicity ResearchPublisher: Springer Science and Business Media LLCVol: 19Issue #: 1Start Page: 63End Page: 72Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s12640-009-9140-zBest OA location URL: https://europepmc.org/articles/pmc3603276?pdf=renderCitation Count: 223
- Glucocerebrosidase mutations are not a common risk factor for Parkinson disease in North Africa2009OPENTitle: Glucocerebrosidase mutations are not a common risk factor for Parkinson disease in North AfricaJournal Name: Neuroscience LettersPublisher: Elsevier BVVol: 477Issue #: 2Start Page: 57End Page: 60Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neulet.2009.11.066Best OA location URL: https://europepmc.org/articles/pmc2970621?pdf=renderCitation Count: 25
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OPENTitle: Dopamine D3 receptor selective ligands with varying intrinsic efficacies at adenylyl cyclase inhibition and mitogenic signaling pathwaysJournal Name: SynapsePublisher: WileyVol: 64Issue #: 3Start Page: 251End Page: 266Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/syn.20725Best OA location URL: https://europepmc.org/articles/pmc3821045?pdf=renderCitation Count: 21
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OPENTitle: Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer’s diseaseJournal Name: BiomarkersPublisher: Informa UK LimitedVol: 14Issue #: 7Start Page: 493End Page: 501Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3109/13547500903108423Best OA location URL: https://europepmc.org/articles/pmc2824250?pdf=renderCitation Count: 107
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OPENTitle: VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's diseaseJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 37Issue #: 2Start Page: 330End Page: 338Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2009.10.011Best OA location URL: https://europepmc.org/articles/pmc2818321?pdf=renderCitation Count: 73
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OPENTitle: Safety and tolerability of putaminal AADC gene therapy for Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 73Issue #: 20Start Page: 1662End Page: 1669Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e3181c29356Best OA location URL: https://europepmc.org/articles/pmc2839805?pdf=renderCitation Count: 401
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OPENTitle: Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: Cross-talk between E3s in the endoplasmic reticulumJournal Name: Biochemical and Biophysical Research CommunicationsPublisher: Elsevier BVVol: 390Issue #: 3Start Page: 758End Page: 762Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bbrc.2009.10.045Best OA location URL: https://europepmc.org/articles/pmc3014991?pdf=renderCitation Count: 54