MJFF Publications

Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways

2024

OPEN

Title: Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways

Author(s): Kelsey Hickey, Alexandra Panov, Enya Miguel Whelan, Tillman Schäfer, Arda Mizrak, Ron R. Kopito, Wolfgang Baumeister, Rubén Fernández‐Busnadiego, J. Wade Harper

Journal Name: Proceedings of the National Academy of Sciences

Publisher: Proceedings of the National Academy of Sciences

Vol: 121

Issue #: 50

Start Page:

End Page:

Publication Date: 2024-12-05

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1073/pnas.2417390121

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Citation Count: 0

The ZFHX3 GGC Repeat Expansion Underlying Spinocerebellar Ataxia Type 4 has a Common Ancestral Founder

2024

OPEN

Title: The ZFHX3 GGC Repeat Expansion Underlying Spinocerebellar Ataxia Type 4 has a Common Ancestral Founder

Author(s): Zhongbo Chen, Pilar Álvarez Jerez, Claire Anderson, Martin Paucar, Jasmaine Lee, Daniel Nilsson, Hannah Macpherson, Annarita Scardamaglia, Kylie Montgomery, John Hardy, Andrew B. Singleton, Arianna Tucci, Katherine D. Mathews, Ying‐Hui Fu, Martin Engvall, José Miguel Laffita‐Mesa, Inger Nennesmo, Anna Wedell, Louis J. Ptáček, Cornelis Blauwendraat, Emil K. Gustavsson, Per Svenningsson, Mina Ryten, Henry Houlden

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 40

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-12-05

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1002/mds.30077

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Citation Count: 0

Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes

2024

OPEN

Title: Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes

Author(s): Jiang‐An Yin, Lukas Frick, Manuel C. Scheidmann, Tingting Liu, Chiara Trevisan, Ashutosh Dhingra, Anna Spinelli, Yancheng Wu, Longping Yao, Dalila Laura Vena, Britta Knapp, Jingjing Guo, Elena De Cecco, Kathi Ging, Andrea Armani, Edward J. Oakeley, Florian Nigsch, Joel Jenzer, Jasmin Haegele, Michal Pikusa, Joachim Täger, Salvador Rodrı́guez-Nieto, Vangelis Bouris, Rafaela Vanin Pinto Ribeiro, Federico Baroni, Manmeet Sakshi Bedi, Scott M. Berry, Marco Losa, Simone Hornemann, Martin Kampmann, Lucas Pelkmans, Dominic Hoepfner, Peter Heutink, Adriano Aguzzi

Journal Name: Nature Biomedical Engineering

Publisher: Springer Science and Business Media LLC

Vol: 9

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-12-04

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41551-024-01278-4

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Citation Count: 2

Slovak database of speech affected by neurodegenerative diseases

2024

OPEN

Title: Slovak database of speech affected by neurodegenerative diseases

Author(s): Milan Rusko, Róbert Sabo, Marián Trnka, Alfréd Zimmermann, Richard Malaschitz, Eugen Ružický, Petra Brandoburová, Viktória Kevická, Matěj Škorvánek

Journal Name: Scientific Data

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-12-04

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41597-024-04171-6

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Citation Count: 0

Validation of Parkinson's Disease Ascertainment in the Veterans Administration Electronic Medical Record

2024

OPEN

Title: Validation of Parkinson's Disease Ascertainment in the Veterans Administration Electronic Medical Record

Author(s): Samuel M. Goldman, Frances M. Weaver, Lishan Cao, Beverly González, Kevin T. Stroupe, Kalea Colletta, Shamil Jugnundan, Ethan G. Brown, Caroline M. Tanner

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 40

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-12-04

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/mds.30075

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Citation Count: 1

A data-driven model of disability progression in progressive multiple sclerosis

2024

OPEN

Title: A data-driven model of disability progression in progressive multiple sclerosis

Author(s): Sara Garbarino, Carmen Tur, Marco Lorenzi, Matteo Pardini, Michele Piana, Antonio Uccelli, Douglas L. Arnold, Bruce Cree, Maria Pia Sormani, Francesca Bovis

Journal Name: Brain Communications

Publisher: Oxford University Press (OUP)

Vol: 7

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-12-03

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1093/braincomms/fcae434

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Citation Count: 1

Cortical complexity alterations in motor subtypes of Parkinson's disease: A surface‐based morphometry analysis of fractal dimension

2024

OPEN

Title: Cortical complexity alterations in motor subtypes of Parkinson's disease: A surface‐based morphometry analysis of fractal dimension

Author(s): Yousef Dehghan, Yashar Sarbaz

Journal Name: European Journal of Neuroscience

Publisher: Wiley

Vol: 60

Issue #: 12

Start Page:

End Page:

Publication Date: 2024-12-03

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1111/ejn.16612

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Citation Count: 0

Identification of isoAsp7-Aβ as a major Aβ variant in Alzheimer’s disease, dementia with Lewy bodies and vascular dementia

2024

OPEN

Title: Identification of isoAsp7-Aβ as a major Aβ variant in Alzheimer’s disease, dementia with Lewy bodies and vascular dementia

Author(s): Sarah Schrempel, Anna Katharina Kottwitz, Anke Piechotta, Kathrin Gnoth, Luca Büschgens, Maike Hartlage‐Rübsamen, Markus Morawski, Mathias Schenk, Martin Kleinschmidt, Geidy E. Serrano, Thomas G. Beach, Agueda Rostagno, Jorge Ghiso, Michael T. Heneka, Jochen Walter, Oliver Wirths, Stephan Schilling, Steffen Roßner

Journal Name: Acta Neuropathologica

Publisher: Springer Science and Business Media LLC

Vol: 148

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-12-03

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1007/s00401-024-02824-9

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Pharmacological targeting of dopamine D1 or D2 receptors evokes a rapid‐onset parkinsonian motor phenotype in mice

2024

OPEN

Title: Pharmacological targeting of dopamine D1 or D2 receptors evokes a rapid‐onset parkinsonian motor phenotype in mice

Author(s): Christian del Agua Villa, Mihai Atudorei, Hartwig R. Siebner, Mattias Rickhag

Journal Name: European Journal of Neuroscience

Publisher: Wiley

Vol: 60

Issue #: 12

Start Page:

End Page:

Publication Date: 2024-12-03

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1111/ejn.16622

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Citation Count: 0

African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1

2024

OPEN

Title: African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1

Author(s): Pilar Álvarez Jerez, Peter Wild Crea, Daniel M. Ramos, Emil K. Gustavsson, Mandy Radefeldt, Andrey Damianov, Mary B. Makarious, Oluwadamilola O. Ojo, Kimberley J. Billingsley, Laksh Malik, Kensuke Daida, Sarah Bromberek, Fangle Hu, Zachary Schneider, Aditya Surapaneni, Julia T. Stadler, Mie Rizig, Huw R. Morris, Caroline B. Pantazis, Hampton L. Leonard, Laurel A. Screven, Yue Qi, M. A. Nalls, Sara Bandrés‐Ciga, John Hardy, Henry Houlden, Celeste Eng, Esteban G. Burchard, Linda Kachuri, Chia-Ho Lin, Douglas L. Black, M. A. Nalls, Andrew B. Singleton, Steffen Fischer, Peter Bauer, Xylena Reed, Mina Ryten, Christian Beetz, Michael E. Ward, Njideka Okubadejo, Cornelis Blauwendraat

Journal Name: Nature Structural & Molecular Biology

Publisher: Springer Science and Business Media LLC

Vol: 31

Issue #: 12

Start Page: 1955

End Page: 1963

Publication Date: 2024-12-01

Open Access(OA) Status: OPEN

License: cc-by, cc-by, cc-by

DOI - Digital Object Identifier: 10.1038/s41594-024-01423-2

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Excessive Daytime Sleepiness as a Risk Factor for Impulse Control Disorders in Parkinson’s Disease

2024

OPEN

Title: Excessive Daytime Sleepiness as a Risk Factor for Impulse Control Disorders in Parkinson’s Disease

Author(s): Xiaohui Tang, Qian Liang, Tao Li, Yi Ouyang, Zhe Huang, X.-F. Tang, Jiayi Jin, Lijia Yu, Xijin Wang

Journal Name: Neuropsychiatric Disease and Treatment

Publisher: Informa UK Limited

Vol: Volume 20

Issue #:

Start Page: 2517

End Page: 2527

Publication Date: 2024-12-01

Open Access(OA) Status: OPEN

License: cc-by-nc

DOI - Digital Object Identifier: 10.2147/ndt.s485339

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Longitudinal correlation of cerebrospinal fluid GFAP and the progression of cognition decline in different clinical subtypes of Parkinson's disease

2024

OPEN

Title: Longitudinal correlation of cerebrospinal fluid GFAP and the progression of cognition decline in different clinical subtypes of Parkinson's disease

Author(s): Yumei Liu, Jing Wang, Fangbo Ning, Guojun Wang, Anmu Xie

Journal Name: Clinical and Translational Science

Publisher: Wiley

Vol: 17

Issue #: 12

Start Page:

End Page:

Publication Date: 2024-12-01

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1111/cts.70111

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Citation Count: 0

Opto-Avoidance-Elevated Plus Maze protocol to study positive or negative valence upon optogenetic stimulation in the mouse brain

2024

OPEN

Title: Opto-Avoidance-Elevated Plus Maze protocol to study positive or negative valence upon optogenetic stimulation in the mouse brain

Author(s): Gian Pietro Serra, François Georges, Åsa Wallén‐Mackenzie

Journal Name: STAR Protocols

Publisher: Elsevier BV

Vol: 5

Issue #: 4

Start Page: 103474

End Page: 103474

Publication Date: 2024-12-01

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1016/j.xpro.2024.103474

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MJF-14 proximity ligation assay detects early non-inclusion alpha-synuclein pathology with enhanced specificity and sensitivity

2024

OPEN

Title: MJF-14 proximity ligation assay detects early non-inclusion alpha-synuclein pathology with enhanced specificity and sensitivity

Author(s): Nanna Møller Jensen, YuHong Fu, Cristine Betzer, Hongyun Li, Sara Elfarrash, Ali H. Shaib, Donatus Krah, Zagorka Vitic, Lasse Reimer, Hjalte Gram, Vladimir L. Buchman, Mark Denham, Silvio O. Rizzoli, Glenda M. Halliday, Poul Henning Jensen

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-29

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41531-024-00841-9

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Citation Count: 0

Seeding activity of skin misfolded tau as a biomarker for tauopathies

2024

OPEN

Title: Seeding activity of skin misfolded tau as a biomarker for tauopathies

Author(s): Zerui Wang, Ling Wu, Maria Gerasimenko, Tricia Gilliland, Syed Zahid Ali Shah, Evalynn Lomax, Yirong Yang, Steven A. Gunzler, Vincenzo Donadio, Rocco Liguori, Bin Xu, Wen‐Quan Zou

Journal Name: Molecular Neurodegeneration

Publisher: Springer Science and Business Media LLC

Vol: 19

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-29

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1186/s13024-024-00781-1

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Citation Count: 0

A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs

2024

OPEN

Title: A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs

Author(s): Caroline Brown, Snehasish Ghosh, Rachel McAllister, Mukesh Kumar, Gerard Walker, Eric I. Sun, Talat Aman, Aniruddha Panda, Shailesh Kumar, Wenxue Li, Jeff Coleman, Yansheng Liu, James E. Rothman, Moitrayee Bhattacharyya, Kallol Gupta

Journal Name: Nature Methods

Publisher: Springer Science and Business Media LLC

Vol: 22

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-11-28

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1038/s41592-024-02517-x

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Enhancement and evaluation for deep learning-based classification of volumetric neuroimaging with 3D-to-2D knowledge distillation

2024

OPEN

Title: Enhancement and evaluation for deep learning-based classification of volumetric neuroimaging with 3D-to-2D knowledge distillation

Author(s): Hyemin Yoon, Do-Young Kang, Sangjin Kim

Journal Name: Scientific Reports

Publisher: Springer Science and Business Media LLC

Vol: 14

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-28

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41598-024-80938-6

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Enhanced Parkin-mediated mitophagy mitigates adverse left ventricular remodelling after myocardial infarction: role of PR-364

2024

OPEN

Title: Enhanced Parkin-mediated mitophagy mitigates adverse left ventricular remodelling after myocardial infarction: role of PR-364

Author(s): Lizhuo Ai, Juliana de Freitas Germano, Chengqun Huang, Marianne Aniag, Savannah Sawaged, Jon Sin, Reetu Thakur, Deepika Rai, Christopher Rainville, David E. Sterner, Yang Song, Honit Piplani, Suresh Kumar, Tauseef R. Butt, Robert M. Mentzer, Aleksandr Stotland, Roberta A. Gottlieb, Jennifer E. Van Eyk

Journal Name: European Heart Journal

Publisher: Oxford University Press (OUP)

Vol: 46

Issue #: 4

Start Page:

End Page:

Publication Date: 2024-11-27

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1093/eurheartj/ehae782

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Citation Count: 2

Incorporating label uncertainty during the training of convolutional neural networks improves performance for the discrimination between certain and inconclusive cases in dopamine transporter SPECT

2024

OPEN

Title: Incorporating label uncertainty during the training of convolutional neural networks improves performance for the discrimination between certain and inconclusive cases in dopamine transporter SPECT

Author(s): Aleksej Kucerenko, Thomas Buddenkotte, Ivayla Apostolova, Susanne Klutmann, Christian Ledig, Ralph Buchert

Journal Name: European Journal of Nuclear Medicine and Molecular Imaging

Publisher: Springer Science and Business Media LLC

Vol: 52

Issue #: 4

Start Page:

End Page:

Publication Date: 2024-11-27

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1007/s00259-024-06988-0

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Citation Count: 0

Associations of motor and neuropsychiatric symptoms with comorbidities in prodromal Parkinson’s disease

2024

OPEN

Title: Associations of motor and neuropsychiatric symptoms with comorbidities in prodromal Parkinson’s disease

Author(s): Jia-Ru Chen, Yan Sun, Ya‐Hui Ma, Lan Tan

Journal Name: Frontiers in Aging Neuroscience

Publisher: Frontiers Media SA

Vol: 16

Issue #:

Start Page:

End Page:

Publication Date: 2024-11-25

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3389/fnagi.2024.1452766

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Citation Count: 0

Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles

2024

OPEN

Title: Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles

Author(s): Selene Seoyun Lee, Livia Civitelli, Laura Parkkinen

Journal Name: eLife

Publisher: eLife Sciences Publications, Ltd

Vol: 13

Issue #:

Start Page:

End Page:

Publication Date: 2024-11-25

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.7554/elife.92775.3

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Citation Count: 1

A multi-region single nucleus transcriptomic atlas of Parkinson’s disease

2024

OPEN

Title: A multi-region single nucleus transcriptomic atlas of Parkinson’s disease

Author(s): N. M. Prashant, John F. Fullard, Tereza Clarence, Deepika Mathur, Clara Casey, Evelyn Hennigan, Marcela Alvia, Joana Krause-Massaguer, Ayled Barreda, David A. Davis, Regina Vontell, Susanna P. Garamszegi, Jeffery M. Vance, Lorelle A. Sang, Michael Chatigny, David Vismer, Barry Landin, David E. Burstein, Donghoon Lee, Georgios Voloudakis, Sabina Berretta, Vahram Haroutunian, William K. Scott, Jaroslav Bendl, Panos Roussos

Journal Name: Scientific Data

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-23

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41597-024-04117-y

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Citation Count: 0

Benchmarking of a multi‐biomarker low‐volume panel for Alzheimer's disease and related dementia research

2024

OPEN

Title: Benchmarking of a multi‐biomarker low‐volume panel for Alzheimer's disease and related dementia research

Author(s): Laura Ibáñez, Menghan Liu, Aleksandra Beric, Jigyasha Timsina, Pat Kohlfeld, Kristy Bergmann, Joey Lowery, Nick Sykora, Brenda Sanchez‐Montejo, Will Brock, John Budde, Randall J. Bateman, Nicolas R. Barthélemy, Suzanne E. Schindler, David M. Holtzman, Tammie L.S. Benzinger, Chengjie Xiong, Rawan Tarawneh, Krista L. Moulder, John C. Morris, Yun Ju Sung, Carlos Cruchaga

Journal Name: Alzheimer's & Dementia

Publisher: Wiley

Vol: 21

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-11-22

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/alz.14413

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Citation Count: 3

A Highly-Efficient, Scalable Pipeline for Fixed Feature Extraction from Large-Scale High-Content Imaging Screens

2024

OPEN

Title: A Highly-Efficient, Scalable Pipeline for Fixed Feature Extraction from Large-Scale High-Content Imaging Screens

Author(s): Gabriel Comolet, N.K. Bose, Jeff Winchell, Alyssa Duren-Lubanski, Tom Rusielewicz, Jordan Goldberg, Grayson Horn, Daniel Paull, Bianca Migliori

Journal Name: iScience

Publisher: Elsevier BV

Vol: 27

Issue #: 12

Start Page: 111434

End Page: 111434

Publication Date: 2024-11-21

Open Access(OA) Status: OPEN

License: cc-by-nc

DOI - Digital Object Identifier: 10.1016/j.isci.2024.111434

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Citation Count: 0

Exome sequencing in Asian populations identifies low-frequency and rare coding variation influencing Parkinson’s disease risk

2024

OPEN

Title: Exome sequencing in Asian populations identifies low-frequency and rare coding variation influencing Parkinson’s disease risk

Author(s): Elaine Guo Yan Chew, Zhehao Liu, Zheng Li, Sun Ju Chung, Michelle Mulan Lian, Moses Tandiono, Yue Jing Heng, Ebonne Ng, Louis C.S. Tan, Wee Ling Chng, Tiak Ju Tan, Esther KL Peh, Ying Swan Ho, Xiao Yin Chen, Erin YT Lim, Chu Hua Chang, Jonavan J. Leong, Ting Xuan Peh, Ling Ling Chan, Yinxia Chao, Wing‐Lok Au, Kumar M. Prakash, Jia Lun Lim, Yi Wen Tay, Vincent Mok, Anne Chan, Juei‐Jueng Lin, Beom S. Jeon, Kyuyoung Song, Clement C. Tham, Chi Pui Pang, Jeeyun Ahn, Kyu Hyung Park, Janey L. Wiggs, Tin Aung, Ai Huey Tan, Azlina Ahmad Annuar, Mary B. Makarious, Cornelis Blauwendraat, M. A. Nalls, Laurie Robak, Roy N. Alcalay, Ziv Gan-Or, Richard Reynolds, Shen‐Yang Lim, Yun Xia, Chiea Chuen Khor, Eng‐King Tan, Zhenxun Wang, Jia Nee Foo

Journal Name: Nature Aging

Publisher: Springer Science and Business Media LLC

Vol: 5

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-11-21

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s43587-024-00760-7

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Citation Count: 3

Genome Aggregation Database Version 4—Allele Frequency Changes and Impact on Variant Interpretation in Dystonia

2024

OPEN

Title: Genome Aggregation Database Version 4—Allele Frequency Changes and Impact on Variant Interpretation in Dystonia

Author(s): Elisabetta Indelicato, Anja Eberl, Sylvia Boesch, Lara M. Lange, Christine Klein, Katja Lohmann, Michael Zech

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 40

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-11-21

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/mds.30066

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Citation Count: 0

Longitudinal decline in DAT binding in Parkinson’s disease: connections with sleep disturbances

2024

OPEN

Title: Longitudinal decline in DAT binding in Parkinson’s disease: connections with sleep disturbances

Author(s): Junli Ren, Haobo Xie, Yiyun Weng, Yaoying Ge, Ruotong Yao, Zihan Jiang, Jinxiu Zhang, Yusheng Zhu, Xiaotong Fu, Junchao Wang, Zijia Liu, Shishu Zhang, Tingxuan Zhang, Guangyong Chen, Dehao Yang

Journal Name: BMC Medicine

Publisher: Springer Science and Business Media LLC

Vol: 22

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-21

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1186/s12916-024-03766-5

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Citation Count: 0

High‐molecular‐weight oligomer tau (HMWoTau) species are dramatically increased in Braak‐stage dependent manner in the frontal lobe of human brains, demonstrated by a novel oligomer Tau ELISA with a mouse monoclonal antibody (APNmAb005)

2024

OPEN

Title: High‐molecular‐weight oligomer tau (HMWoTau) species are dramatically increased in Braak‐stage dependent manner in the frontal lobe of human brains, demonstrated by a novel oligomer Tau ELISA with a mouse monoclonal antibody (APNmAb005)

Author(s): Hiroaki Fukumoto, Tzu‐Huei Kao, Chin‐Yin Tai, Ming‐Kuei Jang, Masaomi Miyamoto

Journal Name: The FASEB Journal

Publisher: Wiley

Vol: 38

Issue #: 22

Start Page:

End Page:

Publication Date: 2024-11-20

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1096/fj.202401704r

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Dopaminergic PET to SPECT domain adaptation: a cycle GAN translation approach

2024

OPEN

Title: Dopaminergic PET to SPECT domain adaptation: a cycle GAN translation approach

Author(s): Leonor Lopes, Fangyang Jiao, Song Xue, Thomas Pyka, Korbinian Krieger, Jingjie Ge, Qian Xu, Rachid Fahmi, Bruce Spottiswoode, Ahmed A. Soliman, Ralph Buchert, Matthias Brendel, Jimin Hong, Yihui Guan, Claudio L. Bassetti, Axel Rominger, Chuantao Zuo, Kuangyu Shi, Ping Wu

Journal Name: European Journal of Nuclear Medicine and Molecular Imaging

Publisher: Springer Science and Business Media LLC

Vol: 52

Issue #: 3

Start Page:

End Page:

Publication Date: 2024-11-19

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1007/s00259-024-06961-x

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Citation Count: 2

Rapid modulation of striatal cholinergic interneurons and dopamine release by satellite astrocytes

2024

OPEN

Title: Rapid modulation of striatal cholinergic interneurons and dopamine release by satellite astrocytes

Author(s): Jeffrey Stedehouder, Bradley M. Roberts, Shinil Raina, Simon Bossi, Alan King Lun Liu, Natalie M. Doig, Kevin McGerty, Peter J. Magill, Laura Parkkinen, Stephanie J. Cragg

Journal Name: Nature Communications

Publisher: Springer Science and Business Media LLC

Vol: 15

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-19

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1038/s41467-024-54253-7

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A worldwide study of subcortical shape as a marker for clinical staging in Parkinson’s disease

2024

OPEN

Title: A worldwide study of subcortical shape as a marker for clinical staging in Parkinson’s disease

Author(s): Max A. Laansma, Yuji Zhao, Eva M. van Heese, Joanna K. Bright, Conor Owens‐Walton, Sarah Al‐Bachari, Tim Anderson, Francesca Assogna, Tim D. van Balkom, Henk W. Berendse, Fernando Cendes, John C. Dalrymple‐Alford, Ines Debove, Michiel F. Dirkx, T. Jason Druzgal, Hedley Emsley, Jean-Paul Fouche, Gaëtan Garraux, Rachel Guimarães, Rick C. Helmich, Joshua Shulman, Odile A. van den Heuvel, Dmitry Isaev, Hojin Kim, Johannes Klein, Christine Löchner, Corey T. McMillan, Tracy R. Melzer, Benjamin T. Newman, Laura M. Parkes, Clelia Pellicano, Fabrizio Piras, Toni L. Pitcher, Kathleen L. Poston, Mario Rango, Letícia Franceschet Ribeiro, Cristiane S. Rocha, Christian Rummel, Lucas S. R. Santos, Reinhold Schmidt, Petra Schwingenschuh, Letizia Squarcina, Dan J. Stein, Daniela Vecchio, Chris Vriend, Jiun‐Jie Wang, Daniel Weintraub, Roland Wiest, Clarissa Lin Yasuda, Neda Jahanshad, Paul R. Thompson, Ysbrand D. van der Werf, Boris A. Gutman

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-18

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00825-9

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Citation Count: 0

Circulating blood circular RNA in Parkinson’s Disease; from involvement in pathology to diagnostic tools in at-risk individuals

2024

OPEN

Title: Circulating blood circular RNA in Parkinson’s Disease; from involvement in pathology to diagnostic tools in at-risk individuals

Author(s): Aleksandra Beric, Yi-Chen Sun, Santiago Sánchez-Vicente, Charissa Martin, Tyler Powell, Ravindra Kumar, Jose Adrian Pardo, Gauri Darekar, Jessie Sanford, Devin Dikec, Carlos Cruchaga, Juan A. Botía, Carlos Cruchaga, Laura Ibáñez

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-18

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41531-024-00839-3

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Citation Count: 0

Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study

2024

OPEN

Title: Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study

Author(s): Philipp Mahlknecht, Simon Leiter, Corinne G.C. Horlings, Katarína Schwarzová, Iris Egner, Heike Stockner, Kathrin Marini, Christoph Theyer, Laura Zamarian, Atbin Djamshidian, Klaus Seppi, Fernando D. Farfán, Alícia Garrido, Soumyabrata Ghosh, Rejko Krueger, Deborah McIntyre, Brit Mollenhauer, Alastair J. Noyce, Claire Pauly, Daniel F. Pilco‐Janeta, Kavita Rege, Venkata Satagopam, Sebastian Schade, Cristina Simonet, Claudia Trenkwalder, Werner Poewe

Journal Name: Movement Disorders Clinical Practice

Publisher: Wiley

Vol: 12

Issue #: 2

Start Page: 203

End Page: 209

Publication Date: 2024-11-18

Open Access(OA) Status: OPEN

License: cc-by-nc

DOI - Digital Object Identifier: 10.1002/mdc3.14264

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Citation Count: 0

Relative sparing of dopaminergic terminals in the caudate nucleus is a feature of rest tremor in Parkinson’s disease

2024

OPEN

Title: Relative sparing of dopaminergic terminals in the caudate nucleus is a feature of rest tremor in Parkinson’s disease

Author(s): Marcelo Mendonça, Pedro Ferreira, Francisco P. M. Oliveira, Raquel Barbosa, Bruna Meira, Durval C. Costa, Albino J. Oliveira‐Maia, Joaquim Alves da Silva

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-18

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41531-024-00818-8

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Citation Count: 0

Peripheral immune cell abundance differences link blood mitochondrial DNA copy number and Parkinson’s disease

2024

OPEN

Title: Peripheral immune cell abundance differences link blood mitochondrial DNA copy number and Parkinson’s disease

Author(s): Longfei Wang, Ji-Ru Han, Liam G. Fearnley, Michael Milton, Haloom Rafehi, J M Reid, Zachary F. Gerring, Shashank Masaldan, Tali Lang, Terence P. Speed, Melanie Bahlo

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-14

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00831-x

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Citation Count: 1

The effects of chemogenetic targeting of serotonin-projecting pathways on L-DOPA-induced dyskinesia and psychosis in a bilateral rat model of Parkinson’s disease

2024

OPEN

Title: The effects of chemogenetic targeting of serotonin-projecting pathways on L-DOPA-induced dyskinesia and psychosis in a bilateral rat model of Parkinson’s disease

Author(s): Natalie Lipari, Ashley Galfano, Shruti Venkatesh, Han Grezenko, Ivette M. Sandoval, Fredric P. Manfredsson, Christopher Bishop

Journal Name: Frontiers in Neural Circuits

Publisher: Frontiers Media SA

Vol: 18

Issue #:

Start Page:

End Page:

Publication Date: 2024-11-14

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3389/fncir.2024.1463941

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Citation Count: 0

Large‐scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity

2024

OPEN

Title: Large‐scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity

Author(s): Fatemeh Seifar, Edward J. Fox, Anantharaman Shantaraman, Yue Liu, Eric B. Dammer, Erica Modeste, Duc M. Duong, Luming Yin, Adam N. Trautwig, Qi Guo, Kaiming Xu, Lingyan Ping, Joseph S. Reddy, Mariet Allen, Zachary Quicksall, Laura Heath, Jo Scanlan, Erming Wang, Minghui Wang, Abby Vander Linden, William L. Poehlman, Xianfeng Chen, Saurabh Baheti, Charlotte C.G. Ho, Thuy Nguyen, Geovanna Yepez, Adriana O. Mitchell, Stephanie R. Oatman, Xue Wang, Minerva M. Carrasquillo, Alexi Runnels, Thomas Beach, Geidy E. Serrano, Dennis W. Dickson, Edward B. Lee, Todd E. Golde, Stefan Prokop, Lisa L. Barnes, Bin Zhang, V. Haroutunian, Marla Gearing, James J. Lah, Philip L. De Jager, David A. Bennett, Anna Greenwood, Nilüfer Ertekin‐Taner, Allan I. Levey, Aliza P. Wingo, Thomas S. Wingo, Nicholas T. Seyfried

Journal Name: Alzheimer's & Dementia

Publisher: Wiley

Vol: 20

Issue #: 12

Start Page:

End Page:

Publication Date: 2024-11-13

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1002/alz.14360

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Citation Count: 6

PathogenicLRRK2mutations cause loss of primary cilia and Neurturin in striatal parvalbumin interneurons

2024

OPEN

Title: PathogenicLRRK2mutations cause loss of primary cilia and Neurturin in striatal parvalbumin interneurons

Author(s): Yu‐En Lin, Ebsy Jaimon, Francesca Tonelli, Suzanne R. Pfeffer

Journal Name: Life Science Alliance

Publisher: Life Science Alliance, LLC

Vol: 8

Issue #: 1

Start Page: e202402922

End Page: e202402922

Publication Date: 2024-11-13

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.26508/lsa.202402922

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Citation Count: 1

Gut Microbial Metabolites and Future Risk of Parkinson's Disease: A Metabolome‐Wide Association Study

2024

OPEN

Title: Gut Microbial Metabolites and Future Risk of Parkinson's Disease: A Metabolome‐Wide Association Study

Author(s): Yujia Zhao, Yunjia Lai, Sirwan K.L. Darweesh, Bastiaan R. Bloem, Lars Forsgren, Johnni Hansen, Verena Katzke, Giovanna Masala, Sabina Sieri, Carlotta Sacerdote, Salvatore Panico, Raúl Zamora‐Ros, María‐José Sánchez, José María Huerta, Marcela Guevara, Ana Vinagre‐Aragón, Paolo Vineis, Christina M. Lill, Gary W. Miller, Susan Peters, Roel Vermeulen

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 40

Issue #: 3

Start Page:

End Page:

Publication Date: 2024-11-12

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/mds.30054

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Citation Count: 0

Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits

2024

OPEN

Title: Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits

Author(s): Ciyang Wang, Chengran Yang, Daniel Western, Muhammad Ali, Yueyao Wang, Chia‐Ling Phuah, John Budde, Lihua Wang, Priyanka Gorijala, Jigyasha Timsina, Agustı́n Ruiz, Pau Pástor, María Victoria Fernández, Daniel J. Panyard, Corinne D. Engelman, Yuetiva Deming, Merçé Boada, Amanda Cano, Pablo García‐González, Neill R. Graff‐Radford, Hiroshi Mori, Jae Hong Lee, Richard J. Perrin, Laura Ibáñez, Yun Ju Sung, Carlos Cruchaga

Journal Name: Nature Genetics

Publisher: Springer Science and Business Media LLC

Vol: 56

Issue #: 12

Start Page: 2685

End Page: 2695

Publication Date: 2024-11-11

Open Access(OA) Status: OPEN

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DOI - Digital Object Identifier: 10.1038/s41588-024-01973-7

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Citation Count: 3

Identification and In Vitro and In Vivo Characterization of KAC-50.1 as a Potential α-Synuclein PET Radioligand

2024

OPEN

Title: Identification and In Vitro and In Vivo Characterization of KAC-50.1 as a Potential α-Synuclein PET Radioligand

Author(s): Dinahlee Saturnino Guarino, Patricia Miranda‐Azpiazu, Dan Sunnemark, Charles S. Elmore, Jonas Bergare, Markus Artelsmair, Gunnar Nordvall, Anton Forsberg Morén, Zhisheng Jia, Miguel A. Cortés González, Robert H. Mach, Kyle C. Wilcox, Sjoerd J. Finnema, Magnus Schou, Andrea Varrone

Journal Name: ACS Chemical Neuroscience

Publisher: American Chemical Society (ACS)

Vol: 15

Issue #: 22

Start Page: 4210

End Page: 4219

Publication Date: 2024-11-11

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1021/acschemneuro.4c00493

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Citation Count: 0

Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease

2024

OPEN

Title: Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease

Author(s): Daniel Western, Jigyasha Timsina, Lihua Wang, Ciyang Wang, Chengran Yang, Carlos Cruchaga, Yueyao Wang, Menghan Liu, Muhammad Ali, Aleksandra Beric, Priyanka Gorijala, Patsy Kohlfeld, John Budde, Allan I. Levey, John C. Morris, Richard J. Perrin, Agustı́n Ruiz, Marta Marquié, Merçé Boada, Itziar de Rojas, Jarod Rutledge, Hamilton Oh, Edward N. Wilson, Yann Le Guen, Lianne M. Reus, Betty M. Tijms, Pieter Jelle Visser, Sven J. van der Lee, Yolande A.L. Pijnenburg, Charlotte E. Teunissen, Marta del Campo, Ignacio Álvarez, Miquel Aguilar, Michael D. Greicius, Pau Pástor, David Pulford, Laura Ibáñez, Tony Wyss‐Coray, Yun Ju Sung, Carlos Cruchaga

Journal Name: Nature Genetics

Publisher: Springer Science and Business Media LLC

Vol: 56

Issue #: 12

Start Page: 2672

End Page: 2684

Publication Date: 2024-11-11

Open Access(OA) Status: OPEN

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DOI - Digital Object Identifier: 10.1038/s41588-024-01972-8

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Citation Count: 8

A framework for translational therapy development in deep brain stimulation

2024

OPEN

Title: A framework for translational therapy development in deep brain stimulation

Author(s): Jia Zhi Chen, Jens Volkmann, Chi Wang Ip

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-08

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41531-024-00829-5

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Citation Count: 0

Novel tools to quantify total, phospho-Ser129 and aggregated alpha-synuclein in the mouse brain

2024

OPEN

Title: Novel tools to quantify total, phospho-Ser129 and aggregated alpha-synuclein in the mouse brain

Author(s): Benjamin G. Trist, Courtney Jade Wright, Alejandra Rangel, Louise Cottle, Asheeta Prasad, Nanna Møller Jensen, Hjalte Gram, Nicolas Dzamko, Poul Henning Jensen, Deniz Kirik

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-08

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00830-y

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Citation Count: 0

The p.Gly2019Ser is a common LRRK2 pathogenic variant among Egyptians with familial and sporadic Parkinson’s disease

2024

OPEN

Title: The p.Gly2019Ser is a common LRRK2 pathogenic variant among Egyptians with familial and sporadic Parkinson’s disease

Author(s): Martina B. William, Sherifa A. Hamed, Ali Shalash, Eman M. Khedr, Mohamed H. Yousef, Shaimaa I El-Jaafary, Gharib Fawi, Asmaa Helmy, Eman Hamid, Mohamed Essam, Hamin Lee, Alina Jama, Mohamed Koraym, Doaa M. Mahmoud, Sara Elfarrash, Yasmin Elsaid, Asmaa Gabr, Nourhan Shebl, Nesreen Abdelwahhab, Tamer Belal, N. El-Sayed, Mohamed Elgamal, Shimaa Elgamal, Salma Ragab, Jaidaa Mekky, Lobna Abdel Aziz Aly, Samir Kanaan Nabhan, Gaafar Ragab, Mohamed Hussein, Mohamed Tharwat Hegazy, Henry Houlden, Mohamed Salama, Mie Rizig

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-06

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41531-024-00826-8

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Citation Count: 0

Predicting Post‐Mortem α‐Synuclein Pathology by the Combined Presence of Probable REM sleep behavior disorder and Hyposmia

2024

OPEN

Title: Predicting Post‐Mortem α‐Synuclein Pathology by the Combined Presence of Probable REM sleep behavior disorder and Hyposmia

Author(s): Cécilia Tremblay, Charles H. Adler, Holly A. Shill, Erika Driver‐Dunckley, Shyamal H. Mehta, Parichita Choudhury, Christine M. Belden, David Shprecher, Joyce Lee‐Iannotti, Alireza Atri, Geidy E. Serrano, Thomas G. Beach

Journal Name: Movement Disorders Clinical Practice

Publisher: Wiley

Vol: 12

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-11-05

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/mdc3.14244

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Citation Count: 1

Respiratory Dysfunction and Abnormal Hypoxic Ventilatory Response in Mild to Moderate Parkinson's Disease

2024

OPEN

Title: Respiratory Dysfunction and Abnormal Hypoxic Ventilatory Response in Mild to Moderate Parkinson's Disease

Author(s): Jules M. Janssen Daalen, Isabel R. Straatsma, Jeroen W.H. van Hees, Auke Weevers, Veerle A. van de Wetering‐van Dongen, Maarten J. Nijkrake, Marjan J. Meinders, Frank H. Bosch, Matthijs Kox, Philip N. Ainslie, Bastiaan R. Bloem, Dick H. J. Thijssen

Journal Name: Movement Disorders Clinical Practice

Publisher: Wiley

Vol: 11

Issue #: 12

Start Page:

End Page:

Publication Date: 2024-11-05

Open Access(OA) Status: OPEN

License: cc-by-nc

DOI - Digital Object Identifier: 10.1002/mdc3.14249

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Citation Count: 0

Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson’s disease overexpressing human alpha synuclein

2024

OPEN

Title: Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson’s disease overexpressing human alpha synuclein

Author(s): Mariangela Massaro Cenere, Marta Tiberi, Emanuela Paldino, Sebastian Luca D’Addario, Mauro Federici, Cecilia Giacomet, Debora Cutuli, Alessandro Matteocci, Francesca Cossa, Beatrice Zarrilli, Nicolas Casadei, Ada Ledonne, Laura Petrosini, Nicola Berretta, Francesca R. Fusco, Valerio Chiurchiù, Nicola Biagio Mercuri

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-11-05

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00824-w

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Citation Count: 0

Dopaminergic Axon Tracts Within a Hyaluronic Acid Hydrogel Encasement to Restore the Nigrostriatal Pathway

2024

OPEN

Title: Dopaminergic Axon Tracts Within a Hyaluronic Acid Hydrogel Encasement to Restore the Nigrostriatal Pathway

Author(s): Wisberty J. Gordián‐Vélez, Kevin D. Browne, Jonathan H. Galarraga, Dimple Chouhan, John E. Duda, Rodrigo A. España, H. Isaac Chen, Jason A. Burdick, D. Kacy Cullen

Journal Name: Advanced Healthcare Materials

Publisher: Wiley

Vol: 14

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-11-04

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/adhm.202402997

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Citation Count: 2

Comparing machine learning and deep learning models to predict cognition progression in Parkinson's disease

2024

OPEN

Title: Comparing machine learning and deep learning models to predict cognition progression in Parkinson's disease

Author(s): Edgar A. Bernal, Shu Yang, Konnor Herbst, Charles S. Venuto

Journal Name: Clinical and Translational Science

Publisher: Wiley

Vol: 17

Issue #: 11

Start Page:

End Page:

Publication Date: 2024-11-01

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1111/cts.70066

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Citation Count: 0

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