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  • Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβ via exosomes
    2018
    Summary Details
    OPEN
    Title: Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβ via exosomes
    Author(s): Javier Pacheco‐Quinto, Dana M. Clausen, Rocío Pérez‐González, Hui Peng, Austin Meszaros, Christopher B. Eckman, Efrat Levy, Elizabeth A. Eckman
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Vol: 33
    Issue #: 3
    Start Page: 3758
    End Page: 3771
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1096/fj.201801319r
    Citation Count: 41
  • Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy
    2015
    Summary Details
    OPEN
    Title: Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy
    Author(s): Markus Mandler, Elvira Valera, Edward Rockenstein, Michael Mante, Harald Weninger, Christina Patrick, Anthony Adame, Sabine Schmidhuber, Radmila Santic, Achim Schneeberger, Walter Schmidt, Frank Mattner, Eliezer Masliah
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-015-0008-9
    Best OA location URL: https://escholarship.org/uc/item/4bm3c0n8
    Citation Count: 142
  • Parkin Mutations Reduce the Complexity of Neuronal Processes in iPSC-Derived Human Neurons
    2014
    Summary Details
    OPEN
    Title: Parkin Mutations Reduce the Complexity of Neuronal Processes in iPSC-Derived Human Neurons
    Author(s): Yong Ren, Houbo Jiang, Zhixing Hu, Kevin Fan, Jun Wang, Stephen Janoschka, Xiaomin Wang, Shaoyu Ge, Jian Feng
    Journal Name: Stem Cells
    Publisher: Oxford University Press (OUP)
    Vol: 33
    Issue #: 1
    Start Page: 68
    End Page: 78
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/stem.1854
    Best OA location URL: https://academic.oup.com/stmcls/article-pdf/33/1/68/42014165/stmcls_33_1_68.pdf
    Citation Count: 101
  • Association of Parkinson disease age of onset with DRD2, DRD3 and GRIN2B polymorphisms
    2015
    Summary Details
    OPEN
    Title: Association of Parkinson disease age of onset with DRD2, DRD3 and GRIN2B polymorphisms
    Author(s): Anhar Hassan, Michael G. Heckman, J. Eric Ahlskog, Zbigniew K. Wszołek, Daniel Serie, Ryan J. Uitti, Jay A. van Gerpen, Michael S. Okun, Sruti Rayaprolu, Owen A. Ross
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 22
    Issue #:
    Start Page: 102
    End Page: 105
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2015.11.016
    Best OA location URL: http://doi.org/10.1016/j.parkreldis.2015.11.016
    Citation Count: 18
  • Peripheral Biomarkers of Parkinson’s Disease Progression and Pioglitazone Effects
    2015
    Summary Details
    OPEN
    Title: Peripheral Biomarkers of Parkinson’s Disease Progression and Pioglitazone Effects
    Author(s): David K. Simon, Tanya Simuni, Jordan J. Elm, Joanne Clark, Allison K. Graebner, Liana Baker, Susan Rebecca Dunlop, Marina E. Emborg, Cornelia Kamp, John C. Morgan, G. Webster Ross, Saloni Sharma, Bernard Ravina
    Journal Name: Journal of Parkinson's Disease
    Publisher: SAGE Publications
    Vol: 5
    Issue #: 4
    Start Page: 731
    End Page: 736
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3233/jpd-150666
    Best OA location URL: http://doi.org/10.3233/JPD-150666
    Citation Count: 29
  • Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway
    2013
    Summary Details
    OPEN
    Title: Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway
    Author(s): Keiichi Inoue, Joanne Rispoli, Lichuan Yang, David MacLeod, M. Flint Beal, Eric Klann, Asa Abeliovich
    Journal Name: PLoS Genetics
    Publisher: Public Library of Science (PLoS)
    Vol: 9
    Issue #: 10
    Start Page: e1003845
    End Page: e1003845
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pgen.1003845
    Best OA location URL: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003845&type=printable
    Citation Count: 19
  • The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer’s Disease
    2016
    Summary Details
    OPEN
    Title: The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer’s Disease
    Author(s): Brittany N. Dugger, Charisse M. Whiteside, Chera L. Maarouf, Douglas G. Walker, Thomas G. Beach, Lucia I. Sue, Angelica Garcia, Travis Dunckley, Bessie Meechoovet, Eric M. Reiman, Alex E. Roher
    Journal Name: Journal of Alzheimer's Disease
    Publisher: SAGE Publications
    Vol: 51
    Issue #: 2
    Start Page: 345
    End Page: 356
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3233/jad-150859
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6074044
    Citation Count: 83
  • Pilot Single-Blind Trial of AbobotulinumtoxinA in Oromandibular Dystonia
    2018
    Summary Details
    OPEN
    Title: Pilot Single-Blind Trial of AbobotulinumtoxinA in Oromandibular Dystonia
    Author(s): Laura Scorr, Michael R. Silver, John Hanfelt, Elaine Sperin, Alan Freeman, Hyder A. Jinnah, Stewart A. Factor
    Journal Name: Neurotherapeutics
    Publisher: Elsevier BV
    Vol: 15
    Issue #: 2
    Start Page: 452
    End Page: 458
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s13311-018-0620-9
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s13311-018-0620-9.pdf
    Citation Count: 10
  • SNCA variants are associated with increased risk for multiple system atrophy
    2009
    Summary Details
    OPEN
    Title: SNCA variants are associated with increased risk for multiple system atrophy
    Author(s): Sonja W. Scholz, Henry Houlden, Claudia Schulte, Manu Sharma, Abi Li, Daniela Berg, Anna Melchers, Reema Paudel, J. Raphael Gibbs, Javier Simón‐Sánchez, Coro Paisán‐Ruíz, José Brás, Jinhui Ding, Honglei Chen, Bryan J. Traynor, Sampath Arepalli, Ryan R. Zonozi, Tamás Révész, Janice L. Holton, Nicholas Wood, Andrew Lees, Wolfgang H. Oertel, Ullrich Wüllner, Stefano Goldwurm, Maria Teresa Pellecchia, Thomas Illig, Olaf Rieß, Hubert H. Fernandez, Ramon L. Rodriguez, Michael S. Okun, Werner Poewe, Gregor K. Wenning, John Hardy, Andrew Singleton, Thomas Gasser
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 65
    Issue #: 5
    Start Page: 610
    End Page: 614
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.21685
    Citation Count: 273
  • Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging
    2014
    Summary Details
    OPEN
    Title: Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging
    Author(s): Michelle M. Mielke, Stephen D. Weigand, Heather J. Wiste, Prashanthi Vemuri, Mary M. Machulda, Davis S. Knopman, Val J. Lowe, Rosebud O. Roberts, Kejal Kantarci, Walter A. Rocca, Clifford R. Jack, Ronald C. Petersen
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Vol: 10
    Issue #: 6
    Start Page: 779
    End Page: 789
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.jalz.2014.09.001
    Citation Count: 29
  • Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
    2009
    Summary Details
    OPEN
    Title: Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
    Author(s): Mari Palgi, Riitta Lindström, Johan Peränen, Petteri Piepponen, Märt Saarma, Tapio I. Heino
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 106
    Issue #: 7
    Start Page: 2429
    End Page: 2434
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0810996106
    Best OA location URL: http://doi.org/10.1073/pnas.0810996106
    Citation Count: 141
  • Neurologist-associated reduction in PD-related hospitalizations and health care expenditures
    2012
    Summary Details
    OPEN
    Title: Neurologist-associated reduction in PD-related hospitalizations and health care expenditures
    Author(s): Allison W. Willis, Mario Schootman, Rebecca Tran, Nathan H. Kung, Bradley Evanoff, Joel S. Perlmutter, Brad A. Racette
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 79
    Issue #: 17
    Start Page: 1774
    End Page: 1780
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e3182703f92
    Best OA location URL: https://n.neurology.org/content/neurology/79/17/1774.full.pdf
    Citation Count: 98
  • Use of a self-rating scale of the nature and severity of symptoms in Parkinson’s Disease (PRO-PD): Correlation with quality of life and existing scales of disease severity
    2017
    Summary Details
    OPEN
    Title: Use of a self-rating scale of the nature and severity of symptoms in Parkinson’s Disease (PRO-PD): Correlation with quality of life and existing scales of disease severity
    Author(s): Laurie K. Mischley, Richard Lau, Noel S. Weiss
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-017-0021-5
    Best OA location URL: https://www.nature.com/articles/s41531-017-0021-5.pdf
    Citation Count: 42
  • Do Stable Patients With a Premorbid Depression History Have a Worse Outcome After Deep Brain Stimulation for Parkinson Disease?
    2011
    Summary Details
    OPEN
    Title: Do Stable Patients With a Premorbid Depression History Have a Worse Outcome After Deep Brain Stimulation for Parkinson Disease?
    Author(s): Michael S. Okun, Samuel S. Wu, Kelly D. Foote, Dawn Bowers, Shilpa Gogna, Catherine C. Price, Irene A. Malaty, Ramon L. Rodriguez, Charles E. Jacobson, Herbert E. Ward
    Journal Name: Neurosurgery
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 69
    Issue #: 2
    Start Page: 357
    End Page: 361
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1227/neu.0b013e3182160456
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3593636
    Citation Count: 23
  • Loss of Thr286 phosphorylation disrupts synaptic CaMKIIα targeting, NMDAR activity and behavior in pre-adolescent mice
    2011
    Summary Details
    OPEN
    Title: Loss of Thr286 phosphorylation disrupts synaptic CaMKIIα targeting, NMDAR activity and behavior in pre-adolescent mice
    Author(s): Richard M. Gustin, Brian C. Shonesy, Stacey L. Robinson, Tyler J. Rentz, Anthony J. Baucum, Nidhi Jalan‐Sakrikar, Danny G. Winder, Gregg D. Stanwood, Roger Colbran
    Journal Name: Molecular and Cellular Neuroscience
    Publisher: Elsevier BV
    Vol: 47
    Issue #: 4
    Start Page: 286
    End Page: 292
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.mcn.2011.05.006
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3149813
    Citation Count: 47
  • Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping
    2015
    Summary Details
    OPEN
    Title: Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping
    Author(s): Jennifer B. Treweek, Ken Y. Chan, Nicholas C. Flytzanis, Bin Yang, Benjamin E. Deverman, Alon Greenbaum, Antti Lignell, Cheng Xiao, Long Cai, Mark S. Ladinsky, Pamela J. Björkman, Charless C. Fowlkes, Viviana Gradinaru
    Journal Name: Nature Protocols
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 11
    Start Page: 1860
    End Page: 1896
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nprot.2015.122
    Citation Count: 258
  • LRRK2 levels in immune cells are increased in Parkinson’s disease
    2017
    Summary Details
    OPEN
    Title: LRRK2 levels in immune cells are increased in Parkinson’s disease
    Author(s): Darcie A. Cook, George T. Kannarkat, Amarallys F. Cintron, Laura M. Butkovich, Kyle Fraser, Jianjun Chang, Nelly Grigoryan, Stewart A. Factor, Andrew B. West, Jeremy M. Boss, Malú G. Tansey
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-017-0010-8
    Best OA location URL: https://doi.org/10.1038/s41531-017-0010-8
    Citation Count: 237
  • Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease
    2017
    Summary Details
    OPEN
    Title: Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease
    Author(s): Reinhard Stöger, Paula J. Scaife, Freya Shephard, Lisa Chakrabarti
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-017-0007-3
    Best OA location URL: https://www.nature.com/articles/s41531-017-0007-3.pdf
    Citation Count: 32
  • Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
    2010
    Summary Details
    OPEN
    Title: Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
    Author(s): Beate Winner, H.L. Melrose, Chen Zhao, K.M. Hinkle, Mei Yue, Caroline Kent, Adam Braithwaite, Sina Ogholikhan, Robert Aigner, Jürgen Winkler, Matthew J. Farrer, F H Gage
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 41
    Issue #: 3
    Start Page: 706
    End Page: 716
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.12.008
    Citation Count: 185
  • Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s Disease
    2009
    Summary Details
    OPEN
    Title: Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s Disease
    Author(s): Wei Zhang, Kester A. Phillips, Albert R. Wielgus, Jie Liu, Alberto Albertini, Fabio A. Zucca, Rudolph Faust, Steven Y. Qian, David S. Miller, Colin F. Chignell, Belinda Wilson, Vernice Jackson‐Lewis, Serge Przedborski, Danielle Joset, John D. Loike, Jau‐Shyong Hong, David Sulzer, Luigi Zecca
    Journal Name: Neurotoxicity Research
    Publisher: Springer Science and Business Media LLC
    Vol: 19
    Issue #: 1
    Start Page: 63
    End Page: 72
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s12640-009-9140-z
    Citation Count: 234
  • The alpha-synuclein 5′untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen
    2011
    Summary Details
    OPEN
    Title: The alpha-synuclein 5′untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen
    Author(s): Jack T. Rogers, Sohan Mikkilineni, Ippolita Cantuti‐Castelvetri, Deborah H. Smith, Xudong Huang, Sanghamitra Bandyopadhyay, Catherine M. Cahill, Maria L. Maccecchini, Debomoy K. Lahiri, Nigel H. Greig
    Journal Name: Journal of Neural Transmission
    Publisher: Springer Science and Business Media LLC
    Vol: 118
    Issue #: 3
    Start Page: 493
    End Page: 507
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00702-010-0513-5
    Citation Count: 71
  • Vascular endothelial growth factor is upregulated by l-dopa in the parkinsonian brain: implications for the development of dyskinesia
    2011
    Summary Details
    OPEN
    Title: Vascular endothelial growth factor is upregulated by l-dopa in the parkinsonian brain: implications for the development of dyskinesia
    Author(s): Elisabet O. Sjöström, Veronica Francardo, Hanna Lindgren, Stephanie E. Sillivan, Sean S. O’Sullivan, Andrew S. Luksik, Fair M. Vassoler, Andrew J. Lees, Christine Konradi, M. Angela Cenci
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 134
    Issue #: 8
    Start Page: 2339
    End Page: 2357
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/brain/awr165
    Best OA location URL: https://academic.oup.com/brain/article-pdf/134/8/2339/13735225/awr165.pdf
    Citation Count: 134
  • Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein
    2014
    Summary Details
    OPEN
    Title: Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein
    Author(s): Xiang Zhang, Hongjun Jin, Prashanth K. Padakanti, Junfeng Li, Hao Yang, Jinda Fan, Robert H. Mach, Paul T. Kotzbauer, Zhude Tu
    Journal Name: Applied Sciences
    Publisher: MDPI AG
    Vol: 4
    Issue #: 1
    Start Page: 66
    End Page: 78
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/app4010066
    Best OA location URL: https://www.mdpi.com/2076-3417/4/1/66/pdf?version=1395063831
    Citation Count: 55
  • Discovery of Potent, Novel Nrf2 Inducers Via Quantum Modeling, Virtual Screening, and In Vitro Experimental Validation
    2012
    Summary Details
    OPEN
    Title: Discovery of Potent, Novel Nrf2 Inducers Via Quantum Modeling, Virtual Screening, and In Vitro Experimental Validation
    Author(s): Tracy P. Williamson, Sara Amirahmadi, Gururaj Joshi, Nikola Kaludov, Martin Martinov, Delinda A. Johnson, Jeffrey A. Johnson
    Journal Name: Chemical Biology & Drug Design
    Publisher: Wiley
    Vol: 80
    Issue #: 6
    Start Page: 810
    End Page: 820
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/cbdd.12040
    Citation Count: 16
  • Increasing the use of mobile technology–derived endpoints in clinical trials
    2018
    Summary Details
    OPEN
    Title: Increasing the use of mobile technology–derived endpoints in clinical trials
    Author(s): William G. Herrington, Jennifer C. Goldsack, Martin Landray
    Journal Name: Clinical Trials
    Publisher: SAGE Publications
    Vol: 15
    Issue #: 3
    Start Page: 313
    End Page: 315
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1177/1740774518755393
    Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/1740774518755393
    Citation Count: 23
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