MJFF Publications

6376 - 6400 of 7916 Results

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Discovery of 3-aminopicolinamides as metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator warheads engendering CNS exposure and in vivo efficacy
2016

OPEN

Title: Discovery of 3-aminopicolinamides as metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator warheads engendering CNS exposure and in vivo efficacy

Author(s): Rocco D. Gogliotti, Darren W. Engers, Pedro M. García-Barrantes, Joseph D. Panarese, Patrick R. Gentry, Anna L. Blobaum, Ryan D. Morrison, J. Scott Daniels, Analisa D. Thompson, Carrie K. Jones, P. Jeffrey Conn, Colleen M. Niswender, Craig W. Lindsley, Corey R. Hopkins

Journal Name: Bioorganic & Medicinal Chemistry Letters

Publisher: Elsevier BV

Vol: 26

Issue #: 12

Start Page: 2915

End Page: 2919

Publication Date: 2016-04-30

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.04.041

Best OA location URL: https://europepmc.org/articles/pmc4899947?pdf=render

Citation Count: 3
How stable are Parkinson's disease subtypes in de novo patients: Analysis of the PPMI cohort?
2016

RESTRICTED

Title: How stable are Parkinson's disease subtypes in de novo patients: Analysis of the PPMI cohort?

Author(s): Tanya Simuni, Chelsea Caspell‐Garcia, Christopher S. Coffey, Shirley Lasch, Caroline M. Tanner, Kenneth Marek

Journal Name: Parkinsonism & Related Disorders

Publisher: Elsevier BV

Vol: 28

Issue #:

Start Page: 62

End Page: 67

Publication Date: 2016-04-30

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.04.027

Best OA location URL:

Citation Count: 147
Morphological Alterations in the Thalamus, Striatum, and Pallidum in Autism Spectrum Disorder
2016

OPEN

Title: Morphological Alterations in the Thalamus, Striatum, and Pallidum in Autism Spectrum Disorder

Author(s): Manuela Schuetze, Min Tae M Park, Ivy YK Cho, Frank P. MacMaster, M. Mallar Chakravarty, Signe Bray

Journal Name: Neuropsychopharmacology

Publisher: Springer Science and Business Media LLC

Vol: 41

Issue #: 11

Start Page: 2627

End Page: 2637

Publication Date: 2016-04-29

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/npp.2016.64

Best OA location URL: https://www.nature.com/articles/npp201664.pdf

Citation Count: 129
Technology in Parkinson's disease: Challenges and opportunities
2016

RESTRICTED

Title: Technology in Parkinson's disease: Challenges and opportunities

Author(s): Alberto J. Espay, Paolo Bonato, Fatta B. Nahab, Walter Maetzler, John Mark Dean, Jochen Klucken, Bjoern M. Eskofier, Aristide Merola, Fay B. Horak, Anthony E. Lang, Ralf Reilmann, Joseph P. Giuffrida, Alice Nieuwboer, Malcolm Horne, Max A. Little, Irene Litvan, Tanya Simuni, E. Ray Dorsey, Michelle A. Burack, Kazuhiko Kubota, Anita Kamondi, Catarina Godinho, Jean‐François Daneault, Georgia Mitsi, Lothar Krinke, J.M. Hausdorff, Bastiaan R. Bloem, Spyros Papapetropoulos

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 31

Issue #: 9

Start Page: 1272

End Page: 1282

Publication Date: 2016-04-29

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1002/mds.26642

Best OA location URL: http://minerva-access.unimelb.edu.au/bitstreams/9b88ef9a-46cf-56a6-adcc-40327184fd3c/download

Citation Count: 477
shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity
2016

OPEN

Title: shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity

Author(s): S. Gonçalves, Diana Macedo, Helena Raquel, Pedro Simões, Flaviano Giorgini, José S. Ramalho, Duarte C. Barral, Luís F. Moita, Tiago F. Outeiro

Journal Name: PLOS Genetics

Publisher: Public Library of Science (PLoS)

Vol: 12

Issue #: 4

Start Page: e1005995

End Page: e1005995

Publication Date: 2016-04-28

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1371/journal.pgen.1005995

Best OA location URL: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005995&type=printable

Citation Count: 76
A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid
2016

OPEN

Title: A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid

Author(s): Niels Kruse, Michael G. Schlossmacher, Walter Schulz‐Schaeffer, Eugeen Vanmechelen, Hugo Vanderstichele, Omar M. A. El‐Agnaf, Brit Mollenhauer

Journal Name: PLOS ONE

Publisher: Public Library of Science (PLoS)

Vol: 11

Issue #: 4

Start Page: e0153564

End Page: e0153564

Publication Date: 2016-04-26

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1371/journal.pone.0153564

Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0153564&type=printable

Citation Count: 5
The BioFIND study: Characteristics of a clinically typical Parkinson's disease biomarker cohort
2016

OPEN

Title: The BioFIND study: Characteristics of a clinically typical Parkinson's disease biomarker cohort

Author(s): Un Jung Kang, Jennifer G. Goldman, Roy N. Alcalay, Tao Xie, Paul Tuite, Claire Henchcliffe, Penelope Hogarth, Amy W. Amara, Samuel Frank, Alice Rudolph, Cynthia Casaceli, Howard Andrews, Katrina Gwinn, Margaret Sutherland, Catherine Kopil, Lona Vincent, Mark Frasier

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 31

Issue #: 6

Start Page: 924

End Page: 932

Publication Date: 2016-04-26

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1002/mds.26613

Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.26613

Citation Count: 51
Free‐water and BOLD imaging changes in Parkinson's disease patients chronically treated with a MAO‐B inhibitor
2016

OPEN

Title: Free‐water and BOLD imaging changes in Parkinson's disease patients chronically treated with a MAO‐B inhibitor

Author(s): Roxana G. Burciu, Edward Ofori, Priyank Shukla, Ofer Pasternak, Jae Woo Chung, Nikolaus R. McFarland, Michael S. Okun, David E. Vaillancourt

Journal Name: Human Brain Mapping

Publisher: Wiley

Vol: 37

Issue #: 8

Start Page: 2894

End Page: 2903

Publication Date: 2016-04-19

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1002/hbm.23213

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945383

Citation Count: 34
Motor and nonmotor heterogeneity of LRRK2‐related and idiopathic Parkinson's disease
2016

RESTRICTED

Title: Motor and nonmotor heterogeneity of LRRK2‐related and idiopathic Parkinson's disease

Author(s): Connie Marras, Roy N. Alcalay, Chelsea Caspell‐Garcia, Jean‐Christophe Corvol, Shuying Liu, John E. Duda, Maurizio Facheris, Rubén Fernández‐Santiago, Carmen Martínez, Tiago Mestre, Rachel Saunders‐Pullman, Claustre Pont‐Sunyer, Eduardo Tolosa, Bjørg Warø

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 31

Issue #: 8

Start Page: 1192

End Page: 1202

Publication Date: 2016-04-19

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1002/mds.26614

Best OA location URL:

Citation Count: 100
Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson’s Disease
2016

OPEN

Title: Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson’s Disease

Author(s): Bruno A. Benítez, Albert A. Davis, Sheng Chih Jin, Laura Ibáñez, Sara Rollinson, Pau Pástor, Jiyoon Choi, Barry Cooper, Joel S. Perlmutter, Carlos Cruchaga

Journal Name: Molecular Neurodegeneration

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2016-04-19

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1186/s13024-016-0097-0

Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/track/pdf/10.1186/s13024-016-0097-0

Citation Count: 61
α‐synuclein genetic variability: A biomarker for dementia in Parkinson disease
2016

OPEN

Title: α‐synuclein genetic variability: A biomarker for dementia in Parkinson disease

Author(s): Ilaria Guella, Daniel M. Evans, Chelsea Szu‐Tu, Ekaterina Nosova, Stephanie Bortnick, Jennifer G. Goldman, John C. Dalrymple‐Alford, Gert J. Geurtsen, Irene Litvan, Owen A. Ross, Lefkos Middleton, Laura Parkkinen, Matthew J. Farrer

Journal Name: Annals of Neurology

Publisher: Wiley

Vol: 79

Issue #: 6

Start Page: 991

End Page: 999

Publication Date: 2016-04-19

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1002/ana.24664

Best OA location URL: http://spiral.imperial.ac.uk/bitstream/10044/1/61098/6/Guella_et%20al_2018%2bSuppl.pdf

Citation Count: 88
A multivariate nonlinear mixed effects model for longitudinal image analysis: Application to amyloid imaging
2016

OPEN

Title: A multivariate nonlinear mixed effects model for longitudinal image analysis: Application to amyloid imaging

Author(s): Murat Bilgel, Jerry L. Prince, Dean F. Wong, Susan M. Resnick, Bruno Jedynak

Journal Name: NeuroImage

Publisher: Elsevier BV

Vol: 134

Issue #:

Start Page: 658

End Page: 670

Publication Date: 2016-04-18

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.neuroimage.2016.04.001

Best OA location URL: https://europepmc.org/articles/pmc4912927?pdf=render

Citation Count: 83
Characterization of RNA isolated from eighteen different human tissues: results from a rapid human autopsy program
2016

OPEN

Title: Characterization of RNA isolated from eighteen different human tissues: results from a rapid human autopsy program

Author(s): Douglas G. Walker, Alexis Whetzel, Geidy E. Serrano, Lucia I. Sue, Lih‐Fen Lue, Thomas G. Beach

Journal Name: Cell and Tissue Banking

Publisher: Springer Science and Business Media LLC

Vol: 17

Issue #: 3

Start Page: 361

End Page: 375

Publication Date: 2016-04-16

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1007/s10561-016-9555-8

Best OA location URL: https://europepmc.org/articles/pmc5026224?pdf=render

Citation Count: 63
Executive functioning and risk-taking behavior in Parkinson’s disease patients with impulse control disorders
2016

OPEN

Title: Executive functioning and risk-taking behavior in Parkinson’s disease patients with impulse control disorders

Author(s): Fanny Pineau, Emmanuel Roze, Lucette Lacomblez, Muriel Bonnet, Marie Vidailhet, Virginie Czernecki, Jean‐Christophe Corvol

Journal Name: Journal of Neural Transmission

Publisher: Springer Science and Business Media LLC

Vol: 123

Issue #: 6

Start Page: 573

End Page: 581

Publication Date: 2016-04-16

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1007/s00702-016-1549-y

Best OA location URL: https://hal.sorbonne-universite.fr/hal-01311564/file/Pineau_2016_Executive.pdf

Citation Count: 15
MRI biomarkers — a precision medicine tool in neurology?
2016

RESTRICTED

Title: MRI biomarkers — a precision medicine tool in neurology?

Author(s): Corey T. McMillan

Journal Name: Nature Reviews Neurology

Publisher: Springer Science and Business Media LLC

Vol: 12

Issue #: 6

Start Page: 323

End Page: 324

Publication Date: 2016-04-15

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1038/nrneurol.2016.51

Best OA location URL: https://europepmc.org/articles/pmc5512159?pdf=render

Citation Count: 8
Clinical-genetic model predicts incident impulse control disorders in Parkinson's disease
2016

OPEN

Title: Clinical-genetic model predicts incident impulse control disorders in Parkinson's disease

Author(s): Julia Kraemmer, Kara Smith, Daniel Weintraub, Vincent Guillemot, Mike A. Nalls, Florence Cormier‐Dequaire, Ivan Moszer, Alexis Brice, Andrew Singleton, Jean‐Christophe Corvol

Journal Name: Journal of Neurology, Neurosurgery & Psychiatry

Publisher: BMJ

Vol: 87

Issue #: 10

Start Page: 1106

End Page: 1111

Publication Date: 2016-04-13

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1136/jnnp-2015-312848

Best OA location URL: https://europepmc.org/articles/pmc5098340?pdf=render

Citation Count: 101
Discovery, Synthesis, and Preclinical Characterization of N-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (VU0418506), a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4)
2016

OPEN

Title: Discovery, Synthesis, and Preclinical Characterization of N-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (VU0418506), a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4)

Author(s): Darren W. Engers, Anna L. Blobaum, Rocco D. Gogliotti, Yiu-Yin Cheung, James M. Salovich, Pedro M. García-Barrantes, J. Scott Daniels, Ryan D. Morrison, Carrie K. Jones, Matthew G. Soars, Xianlu Zhuo, Jeremy Hurley, John E. Macor, Joanne J. Bronson, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins

Journal Name: ACS Chemical Neuroscience

Publisher: American Chemical Society (ACS)

Vol: 7

Issue #: 9

Start Page: 1192

End Page: 1200

Publication Date: 2016-04-13

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1021/acschemneuro.6b00035

Best OA location URL: https://europepmc.org/articles/pmc5031509?pdf=render

Citation Count: 41
Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging
2016

OPEN

Title: Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging

Author(s): Erin L. Abner, Gregory A. Jicha, Leslie M. Shaw, John Q. Trojanowski, Edward J. Goetzl

Journal Name: Annals of Clinical and Translational Neurology

Publisher: Wiley

Vol: 3

Issue #: 5

Start Page: 399

End Page: 403

Publication Date: 2016-04-13

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/acn3.309

Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.309

Citation Count: 60
Mild cognitive impairment in Parkinson's disease versus Alzheimer's disease
2016

OPEN

Title: Mild cognitive impairment in Parkinson's disease versus Alzheimer's disease

Author(s): Lilah M. Besser, Irene Litvan, Sarah E. Monsell, Charles Mock, Sandra Weıntraub, Xiao‐Hua Zhou, Walter A. Kukull

Journal Name: Parkinsonism & Related Disorders

Publisher: Elsevier BV

Vol: 27

Issue #:

Start Page: 54

End Page: 60

Publication Date: 2016-04-10

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.04.007

Best OA location URL: https://europepmc.org/articles/pmc4887313?pdf=render

Citation Count: 25
Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson's disease
2016

OPEN

Title: Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson's disease

Author(s): John N. Caviness, Lih-Fen Lue, Joseph G. Hentz, Christopher T. Schmitz, Charles H. Adler, Holly A. Shill, Marwan N. Sabbagh, Thomas G. Beach, Douglas G. Walker

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 31

Issue #: 7

Start Page: 1012

End Page: 1019

Publication Date: 2016-04-08

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1002/mds.26621

Best OA location URL: https://europepmc.org/articles/pmc4931950?pdf=render

Citation Count: 31
Gene Prioritization for Imaging Genetics Studies Using Gene Ontology and a Stratified False Discovery Rate Approach
2016

OPEN

Title: Gene Prioritization for Imaging Genetics Studies Using Gene Ontology and a Stratified False Discovery Rate Approach

Author(s): Sejal Patel, Min Tae M Park, M. Mallar Chakravarty, Jo Knight

Journal Name: Frontiers in Neuroinformatics

Publisher: Frontiers Media SA

Vol: 10

Issue #:

Start Page:

End Page:

Publication Date: 2016-04-07

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3389/fninf.2016.00014

Best OA location URL: https://www.frontiersin.org/articles/10.3389/fninf.2016.00014/pdf

Citation Count: 8
α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology
2016

OPEN

Title: α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology

Author(s): Josefine Rågård Christiansen, Mads Nikolaj Olesen, Daniel E. Otzen, Marina Romero‐Ramos, Vanesa Sánchez-Guajardo

Journal Name: Journal of Neuroinflammation

Publisher: Springer Science and Business Media LLC

Vol: 13

Issue #: 1

Start Page:

End Page:

Publication Date: 2016-04-07

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1186/s12974-016-0532-8

Best OA location URL: https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-016-0532-8

Citation Count: 33
Personality and reported quality of life in Parkinson's disease
2016

OPEN

Title: Personality and reported quality of life in Parkinson's disease

Author(s): Gregory M. Pontone, Zoltán Mari, Kate Perepezko, Howard D. Weiss, Susan Spear Bassett

Journal Name: International Journal of Geriatric Psychiatry

Publisher: Wiley

Vol: 32

Issue #: 3

Start Page: 324

End Page: 330

Publication Date: 2016-04-05

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1002/gps.4475

Best OA location URL: https://europepmc.org/articles/pmc5333497?pdf=render

Citation Count: 21
Benzoyl chloride derivatization with liquid chromatography–mass spectrometry for targeted metabolomics of neurochemicals in biological samples
2016

OPEN

Title: Benzoyl chloride derivatization with liquid chromatography–mass spectrometry for targeted metabolomics of neurochemicals in biological samples

Author(s): Jenny-Marie T. Wong, Paige A. Malec, Omar S. Mabrouk, Jennifer Ro, Monica Dus, Robert T. Kennedy

Journal Name: Journal of Chromatography A

Publisher: Elsevier BV

Vol: 1446

Issue #:

Start Page: 78

End Page: 90

Publication Date: 2016-04-04

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.chroma.2016.04.006

Best OA location URL: https://europepmc.org/articles/pmc4845038?pdf=render

Citation Count: 217
Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies
2016

OPEN

Title: Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies

Author(s): Anne-Gaëlle Corbillé, Franck Letournel, Jeffrey H. Kordower, John Lee, Elisheva D. Shanes, Michel Neunlist, David G. Muñoz, Pascal Derkinderen, Thomas G. Beach

Journal Name: Acta Neuropathologica Communications

Publisher: Springer Science and Business Media LLC

Vol: 4

Issue #: 1

Start Page:

End Page:

Publication Date: 2016-04-04

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1186/s40478-016-0305-8

Best OA location URL: https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-016-0305-8

Citation Count: 65

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