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  • Widespread sex differences in gene expression and splicing in the adult human brain
    2013
    OPEN
    Title: Widespread sex differences in gene expression and splicing in the adult human brain
    Author(s): Daniah Trabzuni, Adaikalavan Ramasamy, Sabaena Imran, Robert Walker, Colin Smith, Michael E. Weale, John Hardy, Mina Ryten
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/ncomms3771
    Best OA location URL: https://www.nature.com/articles/ncomms3771.pdf
    Citation Count: 281
  • Concordance and Discriminatory Power of Cough Measurement Devices for Individuals With Parkinson Disease
    2013
    OPEN
    Title: Concordance and Discriminatory Power of Cough Measurement Devices for Individuals With Parkinson Disease
    Author(s): Erin Silverman, Giselle Carnaby-Mann, Teresa Pitts, Paul W. Davenport, Michael S. Okun, Christine M. Sapienza
    Journal Name: Chest
    Publisher: Elsevier BV
    Vol: 145
    Issue #: 5
    Start Page: 1089
    End Page: 1096
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1378/chest.13-0596
    Best OA location URL: https://europepmc.org/articles/pmc4011653?pdf=render
    Citation Count: 22
  • A New Method for Quantitative Immunoblotting of Endogenous α-Synuclein
    2013
    OPEN
    Title: A New Method for Quantitative Immunoblotting of Endogenous α-Synuclein
    Author(s): Andrew J. Newman, Dennis J. Selkoe, Ulf Dettmer
    Journal Name: PLoS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 8
    Issue #: 11
    Start Page: e81314
    End Page: e81314
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0081314
    Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0081314&type=printable
    Citation Count: 34
  • Rare variants in LRRK1 and Parkinson's disease
    2013
    OPEN
    Title: Rare variants in LRRK1 and Parkinson's disease
    Author(s): Eva C. Schulte, Daniel C. Ellwanger, Sybille Dihanich, Claudia Manzoni, Katrin Stangl, Barbara Schormair, Elisabeth Graf, Sebastian Eck, Brit Mollenhauer, Dietrich Haubenberger, Walter Pirker, Alexander Zimprich, Thomas Brücke, Peter Lichtner, Annette Peters, Christian Gieger, Claudia Trenkwalder, Hans‐Werner Mewes, Thomas Meitinger, Patrick A. Lewis, Hans H. Klünemann, Juliane Winkelmann
    Journal Name: neurogenetics
    Publisher: Springer Science and Business Media LLC
    Vol: 15
    Issue #: 1
    Start Page: 49
    End Page: 57
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s10048-013-0383-8
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s10048-013-0383-8.pdf
    Citation Count: 29
  • Should impulse control disorders and dopamine dysregulation syndrome be indications for deep brain stimulation and intestinal levodopa?
    2013
    RESTRICTED
    Title: Should impulse control disorders and dopamine dysregulation syndrome be indications for deep brain stimulation and intestinal levodopa?
    Author(s): Michael S. Okun, Daniel Weintraub
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 28
    Issue #: 14
    Start Page: 1915
    End Page: 1919
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25735
    Best OA location URL: https://europepmc.org/articles/pmc3859686?pdf=render
    Citation Count: 29
  • Loss of Leucine-Rich Repeat Kinase 2 (LRRK2) in Rats Leads to Progressive Abnormal Phenotypes in Peripheral Organs
    2013
    OPEN
    Title: Loss of Leucine-Rich Repeat Kinase 2 (LRRK2) in Rats Leads to Progressive Abnormal Phenotypes in Peripheral Organs
    Author(s): Marco A. S. Baptista, Kuldip D. Dave, Mark Frasier, Todd Sherer, Melanie A. Greeley, Melissa J. Beck, Julie S. Varsho, George A. Parker, Cindy Moore, Madeline J. Churchill, Charles K. Meshul, Brian Fiske
    Journal Name: PLoS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 8
    Issue #: 11
    Start Page: e80705
    End Page: e80705
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc0
    DOI - Digital Object Identifier: 10.1371/journal.pone.0080705
    Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0080705&type=printable
    Citation Count: 171
  • Measurement of autophagy flux in the nervous system in vivo
    2013
    OPEN
    Title: Measurement of autophagy flux in the nervous system in vivo
    Author(s): Karen Castillo, V Valenzuela, Soledad Matus, Melissa Nassif, Maritza Oñate, Yerko Fuentealba, Gonzalo Encina, Thergiory Irrazábal, Geoffrey Parsons, Felipe A. Court, Bernard L. Schneider, Donna Armentano, Claudio Hetz
    Journal Name: Cell Death & Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 11
    Start Page: e917
    End Page: e917
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/cddis.2013.421
    Best OA location URL: https://www.nature.com/articles/cddis2013421.pdf
    Citation Count: 104
  • DNAJC13 mutations in Parkinson disease
    2013
    OPEN
    Title: DNAJC13 mutations in Parkinson disease
    Author(s): Carles Vilariño‐Güell, Alex Rajput, Austen J. Milnerwood, Brinda Shah, Chelsea Szu‐Tu, Joanne Trinh, Irene Yu, Mary Joy Encarnacion, Lise N. Munsie, Lucı́a Tapia, Emil K. Gustavsson, Patrick Chou, Igor Tatarnikov, Daniel M. Evans, Frederick T. Pishotta, Mattia Volta, Dayne Beccano-Kelly, Christina Thompson, Takashi Sakurai, Holly E. Sherman, Heather Han, Bruce L. Guenther, Wyeth W. Wasserman, Virginie Bernard, Colin J.D. Ross, Silke Appel‐Cresswell, A. Jon Stoessl, Christopher A. Robinson, Dennis W. Dickson, Owen A. Ross, Zbigniew K. Wszołek, Jan Aasly, Ruey‐Meei Wu, Fayçal Hentati, Rachel A. Gibson, Peter S. McPherson, Martine Girard, Michele L. Rajput, Ali H. Rajput, Matthew J. Farrer
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Vol: 23
    Issue #: 7
    Start Page: 1794
    End Page: 1801
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddt570
    Best OA location URL: https://europepmc.org/articles/pmc3999380?pdf=render
    Citation Count: 281
  • Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease
    2013
    OPEN
    Title: Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease
    Author(s): Laura B. Dunn, G Allen, Adamantios Mamais, Helen Ling, Abi Li, Kate Duberley, Iain P. Hargreaves, Simon Pope, Janice L. Holton, Andrew J. Lees, Simon Heales, Rina Bandopadhyay
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 35
    Issue #: 5
    Start Page: 1111
    End Page: 1115
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd, cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.11.001
    Best OA location URL: https://doi.org/10.1016/j.neurobiolaging.2013.11.001
    Citation Count: 187
  • Tissue transglutaminase in Alzheimer's disease – facts and fiction: a reply to “Tissue transglutaminase is a biochemical marker for Alzheimer's disease”
    2013
    RESTRICTED
    Title: Tissue transglutaminase in Alzheimer's disease – facts and fiction: a reply to “Tissue transglutaminase is a biochemical marker for Alzheimer's disease”
    Author(s): Johannes Wolf, Carsten Jäger, Markus Morawski, Ingolf Lachmann, Peter Schönknecht, Thomas Mothes, Thomas Arendt
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 35
    Issue #: 4
    Start Page: e5
    End Page: e9
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.09.042
    Best OA location URL:
    Citation Count: 13
  • GTP binding controls complex formation by the human ROCO protein MASL1
    2013
    OPEN
    Title: GTP binding controls complex formation by the human ROCO protein MASL1
    Author(s): Sybille Dihanich, Laura Civiero, Claudia Manzoni, Adamantios Mamais, Rina Bandopadhyay, Elisa Greggio, Patrick A. Lewis
    Journal Name: The FEBS Journal
    Publisher: Wiley
    Vol: 281
    Issue #: 1
    Start Page: 261
    End Page: 274
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1111/febs.12593
    Best OA location URL: https://europepmc.org/articles/pmc3995007?pdf=render
    Citation Count: 13
  • Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region
    2013
    OPEN
    Title: Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region
    Author(s): William T. Wissemann, Gully Burns, Cyrus P. Zabetian, Stewart A. Factor, Nikolaos A. Patsopoulos, Bryan Höglund, Cherie L. Holcomb, Ryan J. Donahue, Glenys Thomson, Henry A. Erlich, Haydeh Payami
    Journal Name: The American Journal of Human Genetics
    Publisher: Elsevier BV
    Vol: 93
    Issue #: 5
    Start Page: 984
    End Page: 993
    Publication Date:
    Open Access(OA) Status: OPEN
    License: elsevier-specific: oa user license
    DOI - Digital Object Identifier: 10.1016/j.ajhg.2013.10.009
    Best OA location URL: http://www.cell.com/article/S0002929713004667/pdf
    Citation Count: 157
  • Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation
    2013
    OPEN
    Title: Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation
    Author(s): Claudia Manzoni, Adamantios Mamais, Sybille Dihanich, Phillip McGoldrick, Michael J. Devine, Julia Zerle, Eleanna Kara, Jan‐Willem Taanman, Daniel G. Healy, J.F. Martí-Massó, Anthony H.V. Schapira, Hélène Plun‐Favreau, Sharon A. Tooze, John Hardy, Rina Bandopadhyay, Patrick A. Lewis
    Journal Name: Biochemical and Biophysical Research Communications
    Publisher: Elsevier BV
    Vol: 441
    Issue #: 4
    Start Page: 862
    End Page: 866
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.bbrc.2013.10.159
    Best OA location URL: https://doi.org/10.1016/j.bbrc.2013.10.159
    Citation Count: 80
  • SMG1 Identified as a Regulator of Parkinson’s Disease-Associated alpha-Synuclein through siRNA Screening
    2013
    OPEN
    Title: SMG1 Identified as a Regulator of Parkinson’s Disease-Associated alpha-Synuclein through siRNA Screening
    Author(s): Adrienne Henderson-Smith, Donald Chow, Bessie Meechoovet, Meraj Aziz, Sandra A. Jacobson, Holly A. Shill, Marwan N. Sabbagh, John N. Caviness, Charles H. Adler, Erika Driver‐Dunckley, Thomas G. Beach, Hongwei Yin, Travis Dunckley
    Journal Name: PLoS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 8
    Issue #: 10
    Start Page: e77711
    End Page: e77711
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0077711
    Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0077711&type=printable
    Citation Count: 17
  • Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones
    2013
    OPEN
    Title: Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones
    Author(s): Xianming Deng, Jonathan M. Elkins, Jinwei Zhang, Qingkai Yang, Tatiana Erazo, Néstor Gómez, Hwan Geun Choi, Jinhua Wang, Nicolas Dzamko, Jiing-Dwan Lee, Taebo Sim, Namdoo Kim, Dario R. Alessi, José M. Lizcano, Stefan Knapp, Nathanael S. Gray
    Journal Name: European Journal of Medicinal Chemistry
    Publisher: Elsevier BV
    Vol: 70
    Issue #:
    Start Page: 758
    End Page: 767
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1016/j.ejmech.2013.10.052
    Best OA location URL: https://doi.org/10.1016/j.ejmech.2013.10.052
    Citation Count: 46
  • Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 Diabetes
    2013
    OPEN
    Title: Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 Diabetes
    Author(s): Finja Büchel, Florian Mittag, Clemens Wrzodek, Andreas Zell, Thomas Gasser, Manu Sharma
    Journal Name: PLoS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 8
    Issue #: 10
    Start Page: e78577
    End Page: e78577
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0078577
    Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0078577&type=printable
    Citation Count: 10
  • Over‐expression of an inactive mutant cathepsin D increases endogenous alpha‐synuclein and cathepsin B activity in SH‐SY5Y cells
    2013
    OPEN
    Title: Over‐expression of an inactive mutant cathepsin D increases endogenous alpha‐synuclein and cathepsin B activity in SH‐SY5Y cells
    Author(s): Donna Crabtree, Matthew Dodson, Xiaosen Ouyang, David L. Boone, Qiuli Liang, Mary E. Ballestas, Naomi Fineberg, Jianhua Zhang
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 128
    Issue #: 6
    Start Page: 950
    End Page: 961
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/jnc.12497
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12497
    Citation Count: 38
  • Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutations
    2013
    OPEN
    Title: Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutations
    Author(s): Roy N. Alcalay, Anat Mirelman, Rachel Saunders‐Pullman, Ming‐X Tang, Helen Mejia Santana, Deborah Raymond, Ernest Roos, Martha Orbe‐Reilly, Tanya Gurevich, Anat Bar Shira, Mali Gana Weisz, Kira Yasinovsky, Maayan Zalis, Avner Thaler, Andres Deik, Matthew J. Barrett, Jose Cabassa, Mark Groves, Amelia R. Hunt, Naomi Lubarr, Marta San Luciano, Joan Miravite, Christina A. Palmese, Rivka Sachdev, Harini Sarva, Lawrence Severt, Vicki Shanker, Matthew Swan, Jeannie Soto‐Valencia, Brooke Johannes, Robert Ortega, Stanley Fahn, Lucien Côté, Cheryl Waters, Karen Marder, Blair Ford, Elan D. Louis, Oren Levy, Llency Rosado, Diana Ruiz, Tsvyatko Dorovski, Michael W. Pauciulo, William C. Nichols, Avi Orr‐Urtreger, Laurie J. Ozelius, Lorraine N. Clark, Nir Giladi, Susan Bressman, Karen Marder
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 28
    Issue #: 14
    Start Page: 1966
    End Page: 1971
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25647
    Best OA location URL: https://europepmc.org/articles/pmc3859844?pdf=render
    Citation Count: 128
  • The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation
    2013
    OPEN
    Title: The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation
    Author(s): Eunju Shin, Carlo Lisci, Elisabetta Tronci, Camino Fidalgo, Roberto Stancampiano, Anders Björklund, Manolo Carta
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 62
    Issue #:
    Start Page: 233
    End Page: 240
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2013.09.021
    Best OA location URL: https://lup.lub.lu.se/search/files/1604585/4934203.pdf
    Citation Count: 19
  • Phosphoproteomic evaluation of pharmacological inhibition of leucine‐rich repeat kinase 2 reveals significant off‐target effects of LRRK‐2‐IN‐1
    2013
    OPEN
    Title: Phosphoproteomic evaluation of pharmacological inhibition of leucine‐rich repeat kinase 2 reveals significant off‐target effects of LRRK‐2‐IN‐1
    Author(s): Gregory C. Luerman, Chuong Nguyen, Harry Samaroo, Paula Loos, Hualin Simon Xi, Andres Hurtado‐Lorenzo, Elie Needle, G. Stephen Noell, Paul Galatsis, Y. Bréchet, Kieran F. Geoghegan, Warren D. Hirst
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 128
    Issue #: 4
    Start Page: 561
    End Page: 576
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/jnc.12483
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12483
    Citation Count: 60
  • Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration
    2013
    OPEN
    Title: Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration
    Author(s): Naomi Kouri, Yari Carlomagno, Matthew Baker, Amanda M. Liesinger, Richard J. Caselli, Zbigniew K. Wszołek, Leonard Petrucelli, Bradley F. Boeve, Joseph E. Parisi, Keith A. Josephs, Ryan J. Uitti, Owen A. Ross, Neill R. Graff‐Radford, Michael DeTure, Dennis W. Dickson, Rosa Rademakers
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 127
    Issue #: 2
    Start Page: 271
    End Page: 282
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00401-013-1193-7
    Best OA location URL: https://europepmc.org/articles/pmc3943649?pdf=render
    Citation Count: 72
  • Herp depletion protects from protein aggregation by up-regulating autophagy
    2013
    OPEN
    Title: Herp depletion protects from protein aggregation by up-regulating autophagy
    Author(s): Clara Quiroga, Damián Gatica, Felipe Paredes, Roberto Bravo, Rodrigo Troncoso, Zully Pedrozo, Andrea Rodríguez, Barbra Toro, Mario Chiong, José M. Vicencio, Claudio Hetz, Sergio Lavandero
    Journal Name: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
    Publisher: Elsevier BV
    Vol: 1833
    Issue #: 12
    Start Page: 3295
    End Page: 3305
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1016/j.bbamcr.2013.09.006
    Best OA location URL: https://doi.org/10.1016/j.bbamcr.2013.09.006
    Citation Count: 36
  • Tardive Dyskinesia: Therapeutic Options for an Increasingly Common Disorder
    2013
    OPEN
    Title: Tardive Dyskinesia: Therapeutic Options for an Increasingly Common Disorder
    Author(s): Leslie J. Cloud, Deepti Zutshi, Stewart A. Factor
    Journal Name: Neurotherapeutics
    Publisher: Elsevier BV
    Vol: 11
    Issue #: 1
    Start Page: 166
    End Page: 176
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s13311-013-0222-5
    Best OA location URL: https://europepmc.org/articles/pmc3899488?pdf=render
    Citation Count: 102
  • Dopamine overdose hypothesis: Evidence and clinical implications
    2013
    RESTRICTED
    Title: Dopamine overdose hypothesis: Evidence and clinical implications
    Author(s): David E. Vaillancourt, Daniel Schonfeld, Youngbin Kwak, Nicolaas I. Bohnen, Rachael D. Seidler
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 28
    Issue #: 14
    Start Page: 1920
    End Page: 1929
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25687
    Best OA location URL: https://europepmc.org/articles/pmc3859825?pdf=render
    Citation Count: 135
  • The regulation and deregulation of Wnt signaling by PARK genes in health and disease
    2013
    RESTRICTED
    Title: The regulation and deregulation of Wnt signaling by PARK genes in health and disease
    Author(s): Daniel C. Berwick, Kate Harvey
    Journal Name: Journal of Molecular Cell Biology
    Publisher: Oxford University Press (OUP)
    Vol: 6
    Issue #: 1
    Start Page: 3
    End Page: 12
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1093/jmcb/mjt037
    Best OA location URL: https://academic.oup.com/jmcb/article-pdf/6/1/3/2590207/mjt037.pdf
    Citation Count: 63
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