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  • SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein Level
    2010
    RESTRICTED
    Title: SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein Level
    Author(s): Ignacio Mata, Min Shi, Pinky Agarwal, Kathryn A. Chung, Karen L. Edwards, Stewart A. Factor, Douglas Galasko, Carmen Ginghină, Alida Griffith, Donald S. Higgins, Denise M. Kay, Hojoong Kim, James B. Leverenz, Joseph F. Quinn, John W. Roberts, Ali Samii, Katherine W. Snapinn, Debby W. Tsuang, Dora Yearout, Jing Zhang, Haydeh Payami, Cyrus P. Zabetian
    Journal Name: Archives of Neurology
    Publisher: American Medical Association (AMA)
    Vol: 67
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1001/archneurol.2010.279
    Best OA location URL: https://europepmc.org/articles/pmc3010848?pdf=render
    Citation Count: 149
  • Chaperone-mediated autophagy: machinery, regulation and biological consequences
    2010
    RESTRICTED
    Title: Chaperone-mediated autophagy: machinery, regulation and biological consequences
    Author(s): Wenming Li, Qian Yang, Zixu Mao
    Journal Name: Cellular and Molecular Life Sciences
    Publisher: Springer Science and Business Media LLC
    Vol: 68
    Issue #: 5
    Start Page: 749
    End Page: 763
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00018-010-0565-6
    Best OA location URL:
    Citation Count: 111
  • CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s disease
    2010
    RESTRICTED
    Title: CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s disease
    Author(s): Rudy J. Castellani, Summer L. Nugent, Alan L. Morrison, Xiongwei Zhu, Hyoung Gon Lee, Peggy L.R. Harris, Vladan Bajić, Hari Shanker Sharma, Shu G. Chen, Peter Oettgen, George Perry, Mark A. Smith
    Journal Name: Journal of Neural Transmission
    Publisher: Springer Science and Business Media LLC
    Vol: 118
    Issue #: 1
    Start Page: 23
    End Page: 26
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00702-010-0485-5
    Best OA location URL: https://europepmc.org/articles/pmc3090073?pdf=render
    Citation Count: 13
  • Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    2010
    RESTRICTED
    Title: Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    Author(s): Moussa B. H. Youdim
    Journal Name: Rambam Maimonides Medical Journal
    Publisher: Rambam Health Corporation
    Vol: 1
    Issue #: 2
    Start Page: e0011
    End Page: e0011
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.5041/rmmj.10011
    Best OA location URL: https://www.rmmj.org.il/userimages/13/0/PublishFiles/13Article.pdf
    Citation Count: 8
  • PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
    2010
    RESTRICTED
    Title: PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
    Author(s): Bin Zheng, Zhixiang Liao, Joseph J. Locascio, Kristen A. Lesniak, Sarah S. Roderick, Marla L. Watt, Aron C. Eklund, Yanli Zhang‐James, Peter D. Kim, Michael A. Hauser, Edna Grünblatt, Linda Moran, Silvia Mandel, Peter Riederer, Renee M. Miller, Howard J. Federoff, Ullrich Wüllner, Spyridon Papapetropoulos, Moussa B. H. Youdim, Ippolita Cantuti‐Castelvetri, Anne B. Young, Jeffery M. Vance, Richard L. Davis, John C. Hedreen, Charles H. Adler, Thomas G. Beach, Manuel B. Graeber, Frank A. Middleton, Jean‐Christophe Rochet, Clemens R. Scherzer
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 2
    Issue #: 52
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.3001059
    Best OA location URL: https://europepmc.org/articles/pmc3129986?pdf=render
    Citation Count: 709
  • A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors
    2010
    RESTRICTED
    Title: A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors
    Author(s): Praseeda Mullasseril, Kasper B. Hansen, Katie M. Vance, Kevin K. Ogden, Hongjie Yuan, Natalie L. Kurtkaya, Rose Santangelo, Anna G. Orr, Phuong Le, Kimberly Vellano, Dennis C. Liotta, Stephen F. Traynelis
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/ncomms1085
    Best OA location URL: https://www.nature.com/articles/ncomms1085.pdf
    Citation Count: 143
  • Biomarkers in Parkinson’s disease: a funder’s perspective
    2010
    RESTRICTED
    Title: Biomarkers in Parkinson’s disease: a funder’s perspective
    Author(s): Mark Frasier, Sohini Chowdhury, Jamie L. Eberling, Todd Sherer
    Journal Name: Biomarkers in Medicine
    Publisher: Informa UK Limited
    Vol: 4
    Issue #: 5
    Start Page: 723
    End Page: 729
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2217/bmm.10.89
    Best OA location URL:
    Citation Count: 15
  • LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease
    2010
    RESTRICTED
    Title: LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease
    Author(s): Chen Yao, Rabih El Khoury, Wang Wen, Tara A. Byrd, Elizabeth A. Pehek, Colin Thacker, Xiongwei Zhu, Mark A. Smith, Amy L. Wilson‐Delfosse, Shu G. Chen
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 40
    Issue #: 1
    Start Page: 73
    End Page: 81
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.04.002
    Best OA location URL: https://europepmc.org/articles/pmc2926296?pdf=render
    Citation Count: 126
  • Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
    2010
    RESTRICTED
    Title: Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
    Author(s): Ruth Roberts, Robert A. Smith, Stephen Safe, Csaba Szabó, Ronald B. Tjalkens, Fredika M. Robertson
    Journal Name: Toxicology
    Publisher: Elsevier BV
    Vol: 276
    Issue #: 2
    Start Page: 85
    End Page: 94
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.tox.2010.07.009
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237863
    Citation Count: 181
  • Urate: a novel biomarker of Parkinson’s disease risk, diagnosis and prognosis
    2010
    RESTRICTED
    Title: Urate: a novel biomarker of Parkinson’s disease risk, diagnosis and prognosis
    Author(s): Sara Cipriani, Xiqun Chen, Michael A. Schwarzschild
    Journal Name: Biomarkers in Medicine
    Publisher: Informa UK Limited
    Vol: 4
    Issue #: 5
    Start Page: 701
    End Page: 712
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2217/bmm.10.94
    Best OA location URL: https://europepmc.org/articles/pmc3049925?pdf=render
    Citation Count: 119
  • Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis
    2010
    RESTRICTED
    Title: Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis
    Author(s): Stewart A. Factor, N. Kyle Steenland, Donald S. Higgins, Eric Molho, Denise M. Kay, Jennifer S. Montimurro, Anne Rosén, Cyrus P. Zabetian, Haydeh Payami
    Journal Name: Journal of Neurology, Neurosurgery & Psychiatry
    Publisher: BMJ
    Vol: 82
    Issue #: 5
    Start Page: 564
    End Page: 568
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1136/jnnp.2010.222042
    Best OA location URL: https://europepmc.org/articles/pmc4646086?pdf=render
    Citation Count: 89
  • Estimation of Particulate Mass and Manganese Exposure Levels among Welders
    2010
    RESTRICTED
    Title: Estimation of Particulate Mass and Manganese Exposure Levels among Welders
    Author(s): Angela Hobson, Noah Seixas, David A. Sterling, Brad A. Racette
    Journal Name: The Annals of Occupational Hygiene
    Publisher: Oxford University Press (OUP)
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1093/annhyg/meq069
    Best OA location URL: https://academic.oup.com/annweh/article-pdf/55/1/113/11209915/meq069.pdf
    Citation Count: 44
  • Heterogeneous neuropathological findings in Parkinson’s disease with mild cognitive impairment
    2010
    RESTRICTED
    Title: Heterogeneous neuropathological findings in Parkinson’s disease with mild cognitive impairment
    Author(s): Charles H. Adler, John N. Caviness, Marwan N. Sabbagh, Holly A. Shill, Donald J. Connor, Lucia I. Sue, Virgilio Gerald H. Evidente, Erika Driver‐Dunckley, Thomas G. Beach
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 120
    Issue #: 6
    Start Page: 827
    End Page: 828
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00401-010-0744-4
    Best OA location URL: https://europepmc.org/articles/pmc3100801?pdf=render
    Citation Count: 77
  • Calcium channel blocker use and risk of Parkinson's disease
    2010
    RESTRICTED
    Title: Calcium channel blocker use and risk of Parkinson's disease
    Author(s): Kelly Claire Simon, Xiang Gao, Honglei Chen, Michael A. Schwarzschild, Alberto Ascherio
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 12
    Start Page: 1818
    End Page: 1822
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23191
    Best OA location URL: https://europepmc.org/articles/pmc2939261?pdf=render
    Citation Count: 39
  • Early‐onset L‐dopa‐responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations
    2010
    RESTRICTED
    Title: Early‐onset L‐dopa‐responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations
    Author(s): Coro Paisán-Ruı́z, Rocio Guevara, Monica Federoff, Haşmet Hanağası, Farzad Sina, Elahe Elahi, Susanne A. Schneider, Petra Schwingenschuh, Nin Bajaj, Murat Emre, Andrew Singleton, John Hardy, Kailash P. Bhatia, Sebastian Brandner, Andrew J. Lees, Henry Houlden
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 12
    Start Page: 1791
    End Page: 1800
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23221
    Best OA location URL: https://europepmc.org/articles/pmc6005705?pdf=render
    Citation Count: 228
  • LRRK2 variation and Parkinson's disease in African Americans
    2010
    RESTRICTED
    Title: LRRK2 variation and Parkinson's disease in African Americans
    Author(s): Owen A. Ross, Greggory J. Wilhoite, Justin A. Bacon, Alexandra I. Soto‐Ortolaza, Jennifer M. Kachergus, Stephanie A. Cobb, Andreas Puschmann, Carles Vilariño‐Güell, Matthew J. Farrer, Neill R. Graff‐Radford, James F. Meschia, Zbigniew K. Wszołek
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 12
    Start Page: 1973
    End Page: 1976
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23163
    Best OA location URL: https://europepmc.org/articles/pmc2939165?pdf=render
    Citation Count: 11
  • CSF Aβ42 and tau in Parkinson's disease with cognitive impairment
    2010
    RESTRICTED
    Title: CSF Aβ42 and tau in Parkinson's disease with cognitive impairment
    Author(s): Thomas J. Montine, Min Shi, Joseph F. Quinn, Elaine R. Peskind, Suzanne Craft, Carmen Ginghină, Kathryn A. Chung, Hojoong Kim, Douglas Galasko, Joseph Jankovic, Cyrus P. Zabetian, James B. Leverenz, Jing Zhang
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 15
    Start Page: 2682
    End Page: 2685
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23287
    Best OA location URL: https://europepmc.org/articles/pmc2978754?pdf=render
    Citation Count: 163
  • LRRK2 G2019S mutations are associated with an increased cancer risk in Parkinson disease
    2010
    RESTRICTED
    Title: LRRK2 G2019S mutations are associated with an increased cancer risk in Parkinson disease
    Author(s): Rachel Saunders‐Pullman, Matthew J. Barrett, Kaili Stanley, Marta San Luciano, Vicki Shanker, Lawrence Severt, Amelia R. Hunt, Deborah Raymond, Laurie J. Ozelius, Susan Bressman
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 15
    Start Page: 2536
    End Page: 2541
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23314
    Best OA location URL: https://europepmc.org/articles/pmc2978749?pdf=render
    Citation Count: 62
  • A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys
    2010
    RESTRICTED
    Title: A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys
    Author(s): Daniella Rylander, Hanna Iderberg, Qin Li, Andrzej Dekundy, Jinlan Zhang, Hao Li, Ren Baishen, Wojciech Danysz, Erwan Bézard, M. Angela Cenci
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 39
    Issue #: 3
    Start Page: 352
    End Page: 361
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.05.001
    Best OA location URL:
    Citation Count: 143
  • Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
    2010
    RESTRICTED
    Title: Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
    Author(s): Jonathan Wills, Jessica M. Jones, Thomas Haggerty, Valeriy Duka, Jeffrey N. Joyce, Anita Sidhu
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 225
    Issue #: 1
    Start Page: 210
    End Page: 218
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.06.017
    Best OA location URL: https://europepmc.org/articles/pmc2922478?pdf=render
    Citation Count: 170
  • Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)
    2010
    RESTRICTED
    Title: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)
    Author(s): Darren W. Engers, Patrick R. Gentry, Richard V. Williams, Julie D. Bolinger, C. David Weaver, Usha Menon, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins
    Journal Name: Bioorganic & Medicinal Chemistry Letters
    Publisher: Elsevier BV
    Vol: 20
    Issue #: 17
    Start Page: 5175
    End Page: 5178
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007
    Best OA location URL: https://europepmc.org/articles/pmc2922490?pdf=render
    Citation Count: 26
  • Systemic Weakness After Therapeutic Injections of Botulinum Toxin A
    2010
    RESTRICTED
    Title: Systemic Weakness After Therapeutic Injections of Botulinum Toxin A
    Author(s): Beth E. Crowner, Diego Torres‐Russotto, Alexandre R. Carter, Brad A. Racette
    Journal Name: Clinical Neuropharmacology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 33
    Issue #: 5
    Start Page: 243
    End Page: 247
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1097/wnf.0b013e3181f5329e
    Best OA location URL: https://europepmc.org/articles/pmc3563356?pdf=render
    Citation Count: 79
  • 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
    2010
    RESTRICTED
    Title: 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
    Author(s): R. Jeremy Nichols, Nicolas Dzamko, Nicholas A. Morrice, David G. Campbell, Mária Deák, Alban Ordureau, Thomas Macartney, Yiwei Tong, Jie Shen, Alan R. Prescott, Dario R. Alessi
    Journal Name: Biochemical Journal
    Publisher: Portland Press Ltd.
    Vol: 430
    Issue #: 3
    Start Page: 393
    End Page: 404
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1042/bj20100483
    Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/393/878058/bj4300393.pdf
    Citation Count: 354
  • Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
    2010
    RESTRICTED
    Title: Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
    Author(s): Nicolas Dzamko, Mária Deák, F. Hentati, Alastair D. Reith, Alan R. Prescott, Dario R. Alessi, R. Jeremy Nichols
    Journal Name: Biochemical Journal
    Publisher: Portland Press Ltd.
    Vol: 430
    Issue #: 3
    Start Page: 405
    End Page: 413
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1042/bj20100784
    Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/405/664434/bj4300405.pdf
    Citation Count: 352
  • Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
    2010
    RESTRICTED
    Title: Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
    Author(s): Yong Kyu Lee, Joo‐Ho Shin, Jackalina Vankampen, Leonard Petrucelli, Andrew B. West, Han Seok Ko, Yun Il Lee, Kathleen A. Maguire‐Zeiss, William J. Bowers, Howard J. Federoff, Valina L. Dawson, Ted M. Dawson
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 9
    Start Page: 998
    End Page: 1000
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nm.2199
    Best OA location URL: https://europepmc.org/articles/pmc2935926?pdf=render
    Citation Count: 337
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