-
Charles H. Adler, MD, PhD
… Academy of Neurology Section of Movement Disorders, multiple committees of the Parkinson Study Group, and was a … students, has given many invited lectures and has developed multiple educational programs for the American Academy of …
-
Multiphosphatase Inhibitors as PD Therapeutics
… Objective/Rationale: Parkinson’s disease has multiple genetic and environmental causes. As a result, … or pharmacological tools was found to be protective in multiple animal models of Parkinson’s disease, stroke, …
-
LRRK2 GTPase Validation and Inhibitor Discovery
… GTPase activation in vitro. Final Outcome After testing multiple sources of LRRK2, we found that only LRRK2 isolated … a robust assay for GDP production by LRRK2. We identified multiple hit compounds that reproducibly inhibited GDP …
-
Validation of the 18kDa Translocator Protein as a Novel Immunomodulator to Slow Progression in Parkinson's Disease
… Study Rationale: The immune system in the brain has two distinct modes: mode one is … In Parkinson's disease (PD), we think that the immune system goes into the wrong mode; instead of going into mode …
-
Berkley A. Lynch, PhD
… Inc., Link Medicine and Dotmatics Inc. He has consulted for multiple biotechnology companies and now serves as senior …
-
Penelope Hallett, PhD
… dedicated to work on neurodegenerative diseases, studying multiple aspects of degeneration, protection and cell …