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The Michael J. Fox Foundation Funds $2 Million to Solve Midbrain System Mysteries
June 23, 2004
… signals that produce and maintain the midbrain dopaminergic system that degenerates in Parkinson’s disease. The awards … Patterning and Maintenance of Midbrain Dopaminergic Systems in the Normal and Parkinsonian Brain initiative: …
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Axonopathy induced by overexpression of human -synuclein in the rat nigrostriatal dopamine system
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Clinical Evaluation of LRRK2 Inhibitors on Inflammatory Responses in Crohn's and Parkinson's Diseases
… in CD and PD. … LRRK2 … Inflammation … LRRK2 in the Immune System … Tsuneya Ikezu, MD//PhD …
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Assessment of the Novel Neuronal Synuclein Disease Staging System in Stratifying Dementia with Lewy Bodies Patients
… of "the neuronal synuclein disease (NSD) integrated staging system,” originally designed for PD, in people with … translational research on DLB. We will use the NSD staging system to categorize patients within the E-DLB that have …
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Exploring a Novel Neurotrophic Factor to Protect the Nigrostriatal Dopaminergic System and Alleviate Motor Deficits
… studies to assess the integrity of dopaminergic system. The combined approaches at both structural and …
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New Biological Definition and Proposed Staging System for PD: What it means for Researchers, Industry Professionals and Clinicians
January 29, 2024
… a publication in Lancet Neurology proposing a new staging system for Neuronal Synuclein Disease (NSD). As part of the … several letters raising questions about the staging system and definition of NSD. On June 12, 2024, Lancet …