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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2010
    The Role of LRRK2 in Neurotransmission

    Objective/Rationale: 
    Parkinson disease involves loss of the neurochemical dopamine, and many of the motor symptoms are attributed to a dopamine deficit in the brain region called the striatum. Recent...

  • Novel Approaches to Drug Discovery for Parkinson's Disease, 2010
    Cerium Oxide Nanoparticles in Treatment of Parkinson's Disease

    Promising Outcomes of Original Grant:
    In our 2009-2010 proposal, we hypothesized that pretreatment of a pre-clinical model with cerium oxide nanoparticles would be neuroprotective in the MPTP-pre...

  • MJFF Research Grant, 2010
    MJFF-funded Generation of PD Pre-Clinical Models

    Objective/Rationale: 
    MJFF recognizes the need for predictive pre-clinical models for PD research.  The currently available pre-clinical models do not recapitulate all of the features of PD pathology...

  • MJFF Research Grant, 2010
    MJFF-funded Phenotypic Characterization of PD Pre-Clinical Models

    Objective/Rationale: 
    MJFF recognizes the need for standardizing the characterization of PD pre-clinical models. The currently available pre-clinical models have been characterized at several academic...

  • MJFF Research Grant, 2010
    MJFF-funded Distribution of PD Pre-Clinical Models into Central Repositories

    Objective/Rationale: 
    MJFF recognizes the need for public availability of PD pre-clinical models to ensure greatest access.  A central repository is important for maintaining colonies with consistently...

  • MJFF Research Grant, 2010
    LRRK2 Biochemical Studies (Invitrogen/Nichols Collaboration)

    Objective/Rationale: 
    Mutations in the gene for LRRK2 are one of the most common genetic causes of PD. However, little is known about the biological function of LRRK2 in cells or how LRRK2 biological...

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