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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2009
    Isotopic Stabilization of Dietary Polyunsaturated Fatty Acids as a New Treatment Paradigm for Parkinson's Disease: MPTP and Paraquat Pre-clinical Model Feasibility Studies

    Objective/Rationale:
    Oxidative stress plays a major role in the development of Parkinson’s disease (PD). Essential (available from diet only) polyunsaturated fatty acids (PUFAs) are one of the first...

  • Rapid Response Innovation Awards, 2009
    Targeting Glia in PD with Novel Anti-Inflammatory Therapeutics

    Objective/Rationale:
    Loss of dopamine-producing neurons in Parkinson’s disease (PD) is accompanied by inflammation in surrounding support cells, called glial cells. This inflammatory state in glial...

  • MJFF Research Grant, 2009
    Parkinson's Disease, Ashkenazi Jews and LRRK2: a consortium proposal

    Objective/Rationale:
    Mutations in the LRRK2 gene are the most common genetic cause of classic or typical Parkinson’s disease (PD). One mutation, G2019S, is especially frequent in Jewish (about 14%)...

  • MJFF Research Grant, 2009
    Clinicogenetic Studies of LRRK2 G2019S in Tunisia

    Objective/Rationale:
    Parkinson’s disease (PD) is a prevalent, heterogeneous disorder with a complex, multifactorial etiology. In Tunisia, North Africa, the burden of genetically-defined LRRK2 G2019S...

  • MJFF Research Grant, 2009
    Biomarker Battery Assessment in LRRK2

    Objective/Rationale:
    Parkinson disease (PD) has a pre-clinical phase characterized by death of dopamine neurons in the substantia nigra and other brain regions, which precedes the development of...

  • MJFF Research Grant, 2009
    DAT Imaging in Ashkenazi Jews (AJ) LRRK2 Gene Carriers - a consortium proposal

    Objective/Rationale:
    While most PD is not associated with a specific genetic cause, in some ethnic populations such as Ashkenazi Jews there is a high prevalence of a genetic cause for PD affecting a...

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