The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2013Lung Tissue Model
Study Rationale:
Organovo will leverage its tools and expertise as a 3D biology company to construct a lung model suitable for the screening of certain pharmaceutical compounds. Robust lab-based lung... -
Research Grant, 2013Evaluation of the RXR Agonist Compound IRX4204
Study Rationale:
Drugs that activate the retinoid X nuclear receptor (RXR) have been reported to promote survival of dopaminergic neurons in previously published pre-clinical studies. IRX4204 is a... -
Cognition Biomarkers, 2013[18F]flubatine: A Novel Biomarker of Cognition in Parkinson's Disease
Objective/Rationale:
Mild cognitive impairment and dementia are frequent symptoms of moderate to advanced Parkinson’s disease (PD). Brain positron emission tomography (PET) study findings confirm post... -
Research Grant, 2013CLFB-113: MLK3 Inhibition in Pre-clinical Models of Parkinson's Disease
Objective/Rationale:
Previously inhibitors of mixed lineage kinase 3 (MLK3) showed great promise for treatment of Parkinson’s disease in pre-clinical models, but interest in this area... -
LRRK2 Cohort Consortium, 2013Gender Differences in LRRK2 Mutation and Non-LRRK2 Mutation PD, and Expression of LRRK2 Mutations
Objective/Rationale:
In Western populations, men are approximately 1.5 times more likely to develop Parkinson’s disease (PD) than women. Furthermore, epidemiologic and clinical features of PD vary... -
Clinicopathological Correlations for PD, 2012Identification of Alpha-synuclein Molecular Forms Correlating with Clinicopathology
Promising Outcomes of Original Grant:
We have developed a sensitive method for profiling alpha synuclein and its processed forms (“alpha synucleome”) from minimal clinical model brain tissue using...
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Our funding programs support basic, translational and clinical research from academia and industry.