The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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ASAP CRN Competitive Renewal Opportunity, 2024Parkinson5D: Deconstructing Disease Mechanisms Across Cells, Space and Progression
Study Rationale: Although thousands of DNA variants are linked to Parkinson’s disease (PD), their exact functions are unknown. These variants are in the “dark matter” of our genome and do not lead to...
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ASAP CRN Competitive Renewal Opportunity, 2024Studying the Cortical Pathophysiology of Parkinsonism
Study Rationale: Activity changes in nerve cells in the brain’s cerebral cortex are central to Parkinson’s disease (PD). However, which specific cell types are affected, and how and when their...
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ASAP CRN Competitive Renewal Opportunity, 2024Understanding and Manipulating Cellular and Circuit-level Vulnerability to Neurodegeneration in Parkinson’s Disease
Study Rationale: Many people with Parkinson’s disease (PD) develop untreatable cognitive symptoms due to changes in the brain’s cerebral cortex. These symptoms, which include problems with attention...
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ASAP CRN Competitive Renewal Opportunity, 2024Mapping the Modulatory Landscape Governing Dopamine-acetylcholine Signaling and its Dysregulation in Parkinson’s Disease
Study Rationale: In people with Parkinson's disease (PD), nerve cells that make and release the chemical dopamine start to die. This loss affects the striatum, a brain region that normally receives...
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Research Grant, 2024(SUPPLEMENT) Disparities in Neurocognitive Impairment among Hispanics/Latinos in the US with Parkinson’s Disease: The Role of Cardiovascular Risk
Study Rationale: In the United States, Latinos with Parkinson’s disease (PD) are more likely to have problems with memory, planning and other thinking skills than people with PD of other ethnic/racial...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2024Using A Screening Platform Based on Induced-pluripotent Stem Cells to Study Parkinson’s Disease
Study Rationale: This project represents a supplement to our MJFF project, “Shedding Light on the Dark Genome in Parkinson’s Disease (PD).” For the initial project, we developed a suite of...
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Our funding programs support basic, translational and clinical research from academia and industry.