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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2018
    The Role of Lysosomal Proteins in Inherited Parkinson's Disease Associated with Changes in the GBA gene

    Study Rationale:
    Changes (mutations) in the GBA gene are among the most common and important genetic factors leading to Parkinson's disease (PD). The GBA gene directs the production of the...

  • iPD Program, 2018
    Impact of Genetic Changes Linked to Both Crohn's Disease and Parkinson's Disease on the LRRK2 Protein

    Study Rationale:
    Recent research suggests an about 30 percent higher rate of Parkinson's disease (PD) in people with Crohn's disease (CD) than in those without CD. This could be, at least in part...

  • Research Grant, 2018
    Nanoparticles for Detecting Parkinson's Disease Hallmarks with Magnetic Resonance Imaging

    Study Rationale:
    There is currently no effective imaging agent -- a chemical that reveals signs of disease -- that allows physicians to diagnose Parkinson's disease (PD) at an early stage, to monitor...

  • LRRK2 Tools and Animal Models, 2018
    Tools for Studying Proteins LRRK2 and Rab35

    Study Rationale:
    Mutations in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD). One important function of the LRRK2 protein is to modify other proteins. Previously, we found that...

  • Research Grant, 2018
    Studying Changes in Glucocerebrosidase Activity in People with Parkinson's Disease

    Study Rationale:
    A dysfunction of the glucocerebrosidase (GCase) protein increases the risk of Parkinson's disease (PD). Blood cells called monocytes produce large amounts of this protein. The aim of...

  • Biosample Use Program, 2018
    MicroRNAs as Predictors and Measures of Parkinson's Disease

    Study Rationale:
    MicroRNAs (miRNAs) are molecules that control the production of proteins from genes in the cell. We have found that the blood of people with Parkinson's disease (PD) contains a lower...

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