The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Inducing Aging in Brain Cells to Better Understand Parkinson's Disease
Study Rationale:
Age is the biggest risk factor for Parkinson's disease (PD), with disease incidence rising steeply among persons 60 or older. The reason for this remains unknown. Research suggests... -
Therapeutic Pipeline Program, 2018Developing a Blocker of Alpha-synuclein Production for the Treatment of Parkinson's Disease
Study Rationale:
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). Duplication or triplication of SNCA, a gene responsible for the production of... -
LEAPS, 2018Studying LRRK2 Mutations as a Possible Cause of Waste Buildup in Nerve Cells
Study Rationale:
Health and longevity of brain cells depends on the efficiency of their waste removal process, known as autophagy or self-eating. Cells use autophagy to get rid of unwanted protein... -
Research Grant, 2018The Role of LRRK2 Activity in Inherited Parkinson's Disease
Promising Outcomes of Original Grant:
Mutations (changes) in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD). Previously, we sought to evaluate the connection between a common PD... -
Improved Biomarkers and Clinical Outcome Measures, 2018A Tool for Evaluating Facial Expression for Early Diagnosis of Parkinson's Disease
Study Rationale:
The hypomimia -- decreased facial expression with reduced blinking -- is a major motor sign of Parkinson's disease (PD). This clinical sign indicates movement dysfunction early in the... -
Research Grant, 2018New Imaging Agents for Parkinson's Disease and Related Disorders
Study Rationale:
Imaging is a powerful tool that can be used to visualize the structure and function of the brain in living subjects. In this study, we aim to develop a new brain imaging chemical...
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Our funding programs support basic, translational and clinical research from academia and industry.