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Erika L.F. Holzbaur, PhD

Professor at University of Pennsylvania Perelman School of Medicine

Location: Philadelphia, PA United States

Erika Holzbaur, PhD, is the William Maul Measey professor of physiology at UPenn. She received her BS with high honors in chemistry and history from the College of William and Mary and her PhD in biochemistry from Penn State. Dr.Holzbaur joined the faculty at Penn in 1992, where she is now an endowed professor. She has received a Porter Fellowship, the NINDS Javits Award, the Stanley N. Cohen Biomedical Research Award and the Jane M. Glick Graduate Student Teaching Award from Penn. She was President of ASCB in 2023. Dr.Holzbaur is an outstanding cell biologist with long standing interest in the dynamics of organelle transport and cellular quality control mechanisms like autophagy, with a focus on mitophagy in neurons. Her lab employs 2D culture systems of primary neurons, astrocytes, human iPSC-derived neurons and mouse models to study mechanistic cell biology in the context of neurodegenerative diseases, including Parkinson’s disease and ALS.


Associated Grants

  • Examining the Mechanisms of Mitochondrial Damage Control by PINK1 and Parkin

    2024


  • Studying How Defects in Autophagy Contribute to the Aggregation of Alpha-synuclein in Neurons with LRRK2 Mutations

    2021


  • Mechanisms of Mitochondrial Damage Control by PINK1 and Parkin

    2020


  • Studying LRRK2 Mutations as a Possible Cause of Waste Buildup in Nerve Cells

    2018


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