The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2023(Supplement) PET Imaging Probe Development for Alpha-synuclein
Study Rationale: Alpha-synuclein is a protein that can clump to form Lewy bodies and lewy neurites, which are a hallmark of Parkinson's disease. Being able to identify these clumps in living patients...
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Research Grant, 2023Leveraging Gene Expression Data to Redefine Parkinson’s Disease and the Pathways Driving Disease in Different Individuals
Study Rationale: People with Parkinson’s disease (PD) share some common problems, such as stiffness, slowness of movement and tremors. However, these symptoms vary in severity, and individuals often...
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Parkinson’s Pathway Molecular Data Analysis Program, 2023Characterization of Parkinson’s Disease Clinical Subtypes Using Multiple Immunologic and Genetic Markers
Study Rationale: Parkinson’s disease (PD) is an umbrella term that encompasses a highly heterogeneous domain of clinical manifestations, which makes the development of effective therapeutic strategies...
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Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2023(Supplement) Testing the Neuroprotective Efficacy of Modulating the Lysosomal Gene Atp6v0a1
Study Rationale: The lysosome is a part of a cell involved in degrading and recycling proteins and other large molecules. Parkinson's disease (PD) is linked to lysosomal dysfunction. In this study, we...
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Research Grant, 2023A Phase I Retest Study of Imaging Tracer MODAG-005 in Parkinson’s Disease, Multiple System Atrophy and Healthy Volunteers
Study Rationale: In many neurodegenerative disorders, including Parkinson’s disease (PD) and (MSA), the protein alpha-synuclein is structurally altered and forms aggregates in the brain. These...
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Research Grant, 2023Preclinical Development of Disease-modifying Therapies for Treating Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) is characterized by the hallmark accumulation of toxic clumps of alpha-synuclein, particularly a modified form of the protein called pS129. Acurex has...
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Our funding programs support basic, translational and clinical research from academia and industry.