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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Novel PET Tracer Development Program, 2022
    Discovery of Novel Radiolabeled Tracers for Imaging Microglia Associated with Neuroinflammation in Parkinson’s disease

    Study Rationale: Parkinson´s disease (PD) is associated with neuroinflammation and the activation of microglia, cells that belong to the brain’s immune system. A protein called Colony stimulating...

  • Research Grant, 2022
    Creation and Testing of a Combined Cognitive Score in Parkinson Disease

    Study Rationale: Many different tests of memory and thinking are given to people with Parkinson’s disease (PD), but it is not clear how to use or combine these test scores to best detect early...

  • Cellular Phenotyping in Human iPSCS from the PPMI Cohort, 2022
    Defining Mechanisms in Different Brain Cells that Drive Progression in Parkinson’s Disease

    Study Rationale: The death of dopamine-producing neurons is the defining feature of Parkinson’s disease (PD), leading to the motor symptoms characteristic of the disorder. Given this obvious...

  • Research Grant, 2022
    Assessing the Aggregation of Alpha-synuclein in the Gastrointestinal Tract

    Study Rationale: A growing body of evidence suggests that Parkinson’s disease (PD) may begin in the stomach or elsewhere along the gastrointestinal (GI) tract before spreading to the brain. If this...

  • Research Grant, 2022
    Cognitive Assessment of Non-Human Primate Models of Parkinson's Disease

    Study Rationale: Cognitive impairments cause significant disability for people with Parkinson’s disease (PD). Problems such as reduced attention or difficulty following plans can occur very early in...

  • Translational Pipeline Program, 2022
    Investigating GPR55 as a Novel Neuroprotective Target in Preclinical Models of Parkinson’s Disease

    Study Rationale: Cannabinoids — substances derived from the cannabis plant — have demonstrated neuroprotective properties useful for the treatment of neurodegenerative disorders. Although these...

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