The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Summer 2022 RFP: Accelerating the Translation of Parkinson's Disease Therapies, 2022Validation of a Novel Mitochondrial Drug Target for Parkinson’s Disease
Study Rationale: Mitochondria provide cells with energy, but they also help regulate the flow of large amounts of calcium ions that flood neurons when they are active. In Parkinson’s disease (PD)...
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Spring 2022 RFA: Target Advancement Program - Target Validation, 2022Evaluating an Insulin-degrading Enzyme as a Novel Therapeutic Target for Parkinson’s Disease
Study Rationale: In Parkinson’s disease (PD), the clumping of the protein alpha-synuclein in the brain causes the death of neurons. Recent studies have shown that the insulin-degrading enzyme (IDE)...
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Research Grant, 2022Evaluation of a Monitoring System Based on a Wearable Sensor for Improving Swallowing and Saliva Control in Parkinson’s Disease
Study Rationale: Trouble with swallowing and increased drooling are common issues for people with Parkinson’s disease (PD). These oral symptoms occur in up to 80% of cases. Our prior work showed that...
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Research Grant, 2022Performing a First-In-Human Study of a Retinal Tracer For Alpha-synuclein in Parkinson's Disease
Study Rationale: Like the brain, the retina is part of the central nervous system. We therefore aim to develop a new and simple way to diagnose Parkinson’s disease (PD) via examination of the eye. To...
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Parkinson’s Pathway Molecular Data Analysis Program, 2022Interaction of Mitochondrial Genes and Lifestyle Factors on Age at Onset in Parkinson’s Disease
Study Rationale: Cellular structures called mitochondria are functionally impaired in Parkinson’s disease (PD). How environmental toxins or lifestyle factors influence mitochondrial function and...
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Research Grant, 2022Registry for the Advancement of DBS in Parkinson’s Disease (RAD-PD)
Study Rationale: RAD-PD is a quality improvement patient registry project that will address clinical questions about deep brain stimulation (DBS) therapy that cannot be practically answered via the...
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Our funding programs support basic, translational and clinical research from academia and industry.