The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Research Grant, 2021Exploring the Protective Effect of Modulating Brain Cells’ Electrical Activity in Parkinson’s Disease
Study Rationale: The symptoms of Parkinson’s disease (PD) arise when more than 70% of the dopamine-producing neurons in the brain region regulating movement are lost. This disruption increases the...
-
Fall 2021 RFP: Expanding Biological Understanding of PD, 2021Using Human iPSC to Explore the Role of the STING Pathway in Parkinson's Disease
Study Rationale: Inflammation is recognized as a factor in the progression of Parkinson’s disease (PD). The PD-associated genes PINK1 and Parkin are involved in eliminating damaged cell components...
-
Fall 2021 RFP: Expanding Biological Understanding of PD, 2021Characterizing the Impact of a Protective LRRK2 Variant on Biochemical and Cellular Function
Study Rationale: The LRRK2 gene is one of the most important genes involved in increasing the risk of Parkinson’s disease (PD). Changes in the gene, called mutations, can cause people to develop PD –...
-
Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2021Preclinical Development of Immune-inhibiting Small Molecules as Therapeutics for Parkinson’s Disease
Study Rationale: Brain inflammation plays an important role in the pathology of Parkinson’s disease (PD). One of the key proteins involved in this inflammatory process is STING (stimulator of...
-
Summer 2021 RFP: Expanding Biological Understanding of PD, 2021Assessment of LRRK2 Activity and Neurodegeneration Markers in Postmortem Brain Samples of Idiopathic and LRRK2-associated Parkinson’s Disease
Study Rationale: Genetic variance at the LRRK2 gene locus is associated with risk of Parkinson’s disease (PD). Most evidence suggests that this variation increases the activity of the encoded LRRK2...
-
Outcome Measures, 2021Protective Effect of Immune Gene Subtype in Parkinson’s Disease
Study Rationale: Our genetic studies of Parkinson’s disease (PD) have found a protective effect of an immune gene called HLA-DR, specifically the presence of the HLA-DRB1*04 subtype. We found that HLA...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.