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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2023
    Subtyping Parkinson’s Disease Using Genetic and Intestinal Inflammation Biomarkers

    Study Rationale: Although Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, no drugs are currently available to treat or prevent the condition because the...

  • Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023
    Targeting a Phospholipid Unique to Mitochondrial Membranes as a Therapeutic for Parkinson’s Disease

    Study Rationale: Mitochondria are energy-generating structures vital to the health of all cells. In Parkinson’s disease (PD), mitochondrial dysfunction leads to neuronal degeneration and to the motor...

  • Circuits & Cellular Targets for PD’s Symptoms, 2023
    Unbiased Identification of New Targets for Deep Brain Stimulation to Treat Gait and Balance Impairments in Parkinson’s Disease

    Study Rationale: Over time, people with Parkinson’s disease (PD) develop problems with their ability to walk that can cause serious injuries and curtail their independence. Mice with a particular...

  • Data-Driven Subtyping and Stratification Program, 2023
    Identifying Proteomic Biomarkers for Monitoring the Progression of Parkinson’s Pathophysiology

    Study Rationale: Parkinson’s disease (PD) is often diagnosed at a stage where the disease has progressed significantly, restricting treatment options and limiting the opportunity to understand how the...

  • Circuits & Cellular Targets for PD’s Symptoms, 2023
    Pathophysiology of Neural Circuits Underlying Pain in Prodromal to Advanced Parkinson’s Disease

    Study Rationale: Many people with Parkinson’s disease (PD) suffer from pain that is not managed well by existing therapies. We believe the ineffectiveness of these treatment strategies may be due to a...

  • Translational Pipeline Program, 2023
    Evaluating Use of a Spinal Cord Prosthesis to Alleviate Locomotor Deficits in Parkinson’s Disease

    Study Rationale: Over the past two decades, we have developed a therapy that restores walking after paralysis due to a spinal cord injury. This therapy uses an implanted neurostimulation prosthesis to...

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