The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2016Identification of Genetic Signatures in the Blood as Biomarkers for Parkinson's Disease
Study Rationale:
Epigenetic processes (changes in gene expression), such as DNA methylation (mechanism that cells use to control gene expression), ensure proper functioning of genetic materials in... -
Therapeutic Pipeline Program, 2016Targeting Nicotinic Receptors to Increase Dopamine Function in Parkinson's Disease
Study Rationale:
Nicotinic alpha-6-containing receptors are a specific type of nicotinic receptor (proteins that respond to chemical messengers) expressed on dopamine neurons and are important... -
Research Grant, 2016Rab Detection Initiative
Study Rationale:
The LRRK2 enzyme regulates proteins through a process called phosphorylation. The LRRK2 gene, which is mutated in familial Parkinson's disease (PD), an inherited form of PD, can... -
Target Advancement Program, 2016Protecting Dopamine Neurons in Parkinson's Disease
Study Rationale:
Parkinson's disease (PD) is caused by death of dopamine-containing cells in the brain. We discovered that a protein known as RGS6 is expressed in these cells in pre-clinical models of... -
Target Advancement Program, 2016Imaging Endogenous LRRK2 Cells
Study Rationale:
The leucine-rich repeat kinase 2 (LRRK2) protein is an important player that contributes to Parkinson's disease (PD). Unfortunately, LRRK2 is a large and complex protein that is... -
Access to Data and Biospecimens, 2016Single Molecule Detection of Oligomers in Cerebrospinal Fluid
Study Rationale:
We have developed a novel method for detecting aggregations (clumps) of proteins (specifically, alpha-synuclein) in the spinal fluid of those with Parkinson's disease (PD). We seek to...
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Our funding programs support basic, translational and clinical research from academia and industry.