The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2016Identification of Epigenetic Signatures in Blood as Biomarkers for Parkinson's Disease
Study Rationale:
Epigenetic processes (changes in gene expression), such as DNA methylation (mechanism that cells use to control gene expression), ensure proper functioning of genetic materials in... -
Biomarker Development, 2015Development of Novel, Small Molecule Compounds as PET Tracers for Synucleinopathies
Study Rationale:
Our project aims to develop a brain imaging agent for alpha-synuclein, a key protein involved in Parkinson’s disease (PD) pathology. Such an agent will help (i) diagnose PD earlier,... -
Access to Data and Biospecimens, 2015Lysosomal Enzyme Activity and GBA1 Genotyping in Parkinson’s Disease
Study Rationale:
The dysfunction of the systems responsible for the clearance of the protein alpha-synuclein plays a major role in Parkinson’s disease (PD). The lysosome is an... -
Therapeutic Pipeline Program, 2015Utilization of Aptamers to Prevent Protein Aggregation in Parkinson’s Disease
Objective/Rationale:
The abnormal aggregation of a protein known as alpha-synuclein appears to play a critical role in Parkinson's disease. This project will explore a new type of... -
Improved Biomarkers and Clinical Outcome Measures, 2015Developing Progression Markers of Parkinson’s Disease with Multimodal Structural MRI of Substantia Nigra and Locus Coeruleus
Study Rationale:
Substantia nigra pars compacta (SNpc) and locus coeruleus (LC) are key brain areas involved in Parkinson’s disease. The loss of important chemicals (dopamine and norepinephrine) made... -
Research Grant Supplement, 2015Identification of the Parkin-binding Domain for SLP-2 as a Potential Therapeutic Target Supplement
Promising Outcomes of Original Grant:
The objective of our Rapid Response Innovation Awards-supported project was to identify the parkin domain that interacts with Stomatin-like protein 2 (SLP-2), a...
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Our funding programs support basic, translational and clinical research from academia and industry.