The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2012A Small Molecule Approach to Correct Striatal Cholinergic Interneuron Dysfunction
Objective/Rationale:
There is growing evidence that cholinergic interneurons (ChIs) in the striatum undergo maladaptive biochemical changes leading to their hyperactivation under conditions of... -
LRRK2 Biology LEAPS, 2012Protein Interaction Network Analysis and Pathway Modeling for LRRK2
Objective/Rationale:
Mutations in the Leucine-rich Repeat Kinase 2 gene (LRRK2) are the single most common cause for inherited Parkinson's disease (PD). LRRK2 is a large protein consisting of... -
MJFF Research Grant, 2012Neuroimaging Markers Predict Cognitive Decline in PD
Promising Outcomes of Original Grant:
Excessive amounts of amyloid in brain tissue are believed to be toxic and cause the neuronal damage that results in dementia. Amyloid deposits can be detected in... -
MJFF Research Grant, 2012Mechanisms of Parkin Recruitment and Mitophagy
Promising Outcomes of Original Grant:
The protein Parkin is thought to be required for the maintenance of healthy mitochondria, critical subcellular organelles that govern cellular energy production... -
Rapid Response Innovation Awards, 2012Is the Xenomitochondrial Pre-clinical model an ‘Ideal’ Parkinson’s Disease Model?
Objective/Rationale:
The lack of a pre-clinical model that exhibits key features of human Parkinson’s disease is an impediment to research progress. In this project we will determine whether a novel... -
Rapid Response Innovation Awards, 2012Mifunctional Cembranoids for Therapy of Parkinson’s Disease
Objective/Rationale:
Although considerable achievements have been made in the understanding of pathophysiology of Parkinson’s disease (PD), there are still limited effective approaches available for...
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Our funding programs support basic, translational and clinical research from academia and industry.