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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2011
    Just in Time Pre-clinical Resource for Evaluating Symptoms & Side Effects and/or Dyskinesia Treatments

    Objective/Rationale:
    There is a clear need for the development of novel treatments to better manage the symptoms of Parkinson’s disease. While current treatments address some of the motor symptoms of...

  • MJFF Research Grant, 2011
    Generation of Synthetic Alpha-synuclein for the PD Research Community

    Objective/Rationale:
    Despite increasing evidence linking specific modifications to alpha-synuclein (alpha-syn), alpha-synuclein aggregation, and Lewy body (LB) formation, little is still known...

  • LRRK2 Target Engagement Ligand, 2011
    Discovery of LRRK2 Target Engagement Ligands to be Used in Imaging Studies

    Objective/Rationale: 
    LRRK2 is an emerging target for discovery of a neuroprotective agent for treatment of PD. Multiple mutations within the LRRK2 gene are associated with PD and many of these have...

  • LRRK2 Target Engagement Ligand, 2011
    LRRK2 Target Engagement Ligand

    Objective/Rationale: 
    Target engagement ligands, also known as imaging agents, are useful tools in the development of drugs and this project seeks to develop such a tool for Leucine Rich Repeat Kinase...

  • Rapid Response Innovation Awards, 2011
    Regulated GDNF Gene Therapy: a Novel Regulatory System Based on Protein Degradation

    Objective/Rationale:
    Gene therapy may offer effective treatments to patients. Delivering genes to cells in the body has the potential of letting the patient’s cells treat themselves. In the case of...

  • MJFF Research Grant, 2011
    Global Estimates for the Role of LRRK2 Variation in Parkinson's Disease Susceptibility

    Promising Outcomes of Original Grant:
    Our original goal was to resolve the role of known LRRK2 coding variants in susceptibility to Parkinson’s disease. Our studies have nominated risk factors for...

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Our funding programs support basic, translational and clinical research from academia and industry.

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