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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Critical Challenges in PD: Alpha-synuclein Neuroimaging, 2009
    Utility of the Amyloid Ligand [18F]FDDNP in Human PET Imaging in Parkinson Disease

    Objective/Rationale:
    Biomarkers of Parkinson disease are sorely needed for the assessment of disease status so that they may be used to design more efficient and informative clinical trials of disease...

  • Critical Challenges in PD: Alpha-synuclein Neuroimaging, 2009
    18F-labeled Alpha-Synuclein Ligands for PET Imaging of Lewy Bodies

    Objective/Rationale:
    The Avid-ProteoTech program aims at identifying radiopharmaceuticals for PET imaging of Lewy bodies in the human brain. Lewy bodies, formed by aggregates of alpha-synuclein, are a...

  • Critical Challenges in PD: Alpha-synuclein Neuroimaging, 2009
    A Strategy to Develop a Radiotracer Targeting Alpha-Synuclein

    Objective/Rationale: 
    Alpha-synuclein is a protein that is found in nerve cells of patients with PD and therefore provides a potential target for methods designed to monitor the disease process in PD...

  • Rapid Response Innovation Awards, 2009
    H5N1 Influenza Virus as a Etiological Agent in Parkinson's Disease

    Objective/Rationale:
    There is a significant literature (mostly based on cases from the Spanish Influenza outbreak of 1918) that has documented Parkinson’s disease occurring, following exposure to...

  • Rapid Response Innovation Awards, 2009
    Effect of novel sirtuin inhibitors on alpha-synuclein toxicity in a Parkinson disease pre-clinical model

    Objective/Rationale: 
    The objective of the proposed research is to test the ability of novel sirtuin inhibitors to protect against dopamine neuron toxicity in a pre-clinical model of Parkinson's...

  • Rapid Response Innovation Awards, 2009
    Rational Vectors For PD

    Objective/Rationale:
    The project is hot on the trail of key suspect players in Parkinson’s disease. The output of an innovative screening process put forth a handful of candidate enzymes in a lower...

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