The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2007CDNF - A Novel Conserved Neurotrophic Factor that Protects Midbrain Dopaminergic Neurons in vivo
Promising Outcomes of Original Grant:
Future treatment of Parkinson’s disease aim at therapies which would stop the progress of the disease and restore the function of injured dopamine nerves in the... -
Target Validation, 2007Targeting Urate: A Molecular Correlate of Both Risk and Progression in PD
Objective/Rationale:
Urate (a natural antioxidant, caffeine analog and DNA metabolite) is the first molecule linked to both the risk of typical Parkinson’s disease and its rate of progression. Higher... -
Rapid Response Innovation Awards, 2007Potential Utility of Novel CNS-active Experimental Therapeutics for Parkinson's Disease
Objective/Rationale:
Evidence suggests that overproduction of inflammatory molecules, called proinflammatory cytokines, from glial cells in the brain can contribute to nerve cell death and accelerate... -
Rapid Response Innovation Awards, 2007Understanding the Molecular and Functional Changes of CB1/D2/A2A Receptor Complexes in the Hemi-parkinsonian Pre-clinical Model
Objective/Rationale:
Future therapies in Parkinson’s disease (PD) may derive from the existence of intramembrane heteromeric receptor complexes containing the dopamine D2 receptor. The ability of... -
Rapid Response Innovation Awards, 2007A Novel Strategy for the Selection and Transplantation of Dopamine-Specified Human Embryonic Stem Cells
In parkinson’ disease (PD), neurodegeneration is largely confined to one discrete group of nerve cells that produce the chemical dopamine (DA). Since the death of most DA neurons almost always...
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Rapid Response Innovation Awards, 2007Gene-Environment Interactions in Parkinson's Disease
Objective/Rationale:
Although the causes of sporadic Parkinson’s disease are still unknown, recent evidence suggests that exposure to pesticides increases the risk for PD. However, most of these...
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Our funding programs support basic, translational and clinical research from academia and industry.