The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2004Finding genetic risk factors for Parkinson’s disease in genetically isolated populations
What causes Parkinson's disease is largely unknown but both environmental factors and genetic risk factors play a role. Over the years researchers have identified mutations in genes that are...
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Community Fast Track, 2004Mechanisms of HIPK2-dependent Survival & Differentiation of Midbrain Dopaminergic Neurons - a Chemical Genetic Target for Parkinson's Disease
Regulation of gene expression is critical for neuronal development, survival, differentiation, and axon/dendritic arborization. While several transcription factors have been shown to be important for...
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Community Fast Track, 2004Vaccine-induced Neuroprotection in an Animal Model of Parkinson's Disease
There is a growing appreciation that immune responses can significantly improve neuronal survival after injury or in neurodegenerative diseases. Immune-deficient mice have reduced neurorepair...
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The Role of Inflammation in Parkinson's Disease, 2003Inflammatory Mechanisms & PD Risk: A Discordant Twin Pairs Case-Control Study
The cause of Parkinson’s disease is unknown. A genetic cause is identified in only a small percentage of cases. We believe that environmental factors play an important role in most cases of PD. While...
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Molecular Mechanisms of Dyskinesia in Parkinson's Disease, 2003The Role of Abnormal Gap Junction Communication in the Generation of Levodopa-induced Dyskinesia in Parkinson's Disease
We hypothesize that enhanced gap junction communication (GJC) plays an unheralded and important role in the neural mechanisms underlying levodopa-induced dyskinesia (LID). Gap junctions are a special...
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Molecular Mechanisms of Dyskinesia in Parkinson's Disease, 2003A Trial of Low Frequency Repetitive Transcranial Magnetic Stimulation for Treatment of Dyskinesia
Levodopa-induced dyskinesia (LID) is a major source of disability of many patients with Parkinson's disease (PD). LID may be associated with increased activity of the part of the brain that mediates...
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Our funding programs support basic, translational and clinical research from academia and industry.