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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Fast Track, 2001
    Generation and Analysis of Conditional Pre-Clinical Model Mutants for BNDF and GDNF Receptors

    Parkinson's disease results largely from the degeneration of dopamincergic neurons in the substantia nigra pars compacta. The reason for the successive death of these neurons is not known so far...

  • Fast Track, 2001
    rAAV-ribozyme Mediated Parkin Knockdown as a Pre-clinical Model of Parkinson's Disease

    Parkinson's disease is characterized by a series of debilitating motor abnormalities that worsen over time. The motor symptoms of Parkinson's disease are largely the result of the specific progressive...

  • Fast Track, 2001
    Molecular and Genetic Analysis of Parkin in the Pathogenesis of Parkinson's Disease

    The ultimate goal of this proposal is to create new, more effective means of preventing, diagnosing and treating neural degeneration associated with Parkinson's disease (PD). PD is a chronic...

  • Fast Track, 2001
    A Gene Therapy Development for PD in Synuclein Transgenic Mice

    The number of people with Parkinson's disease (PD) is increasing rapidly because life expectancy of people in developed countries continues to rise. Without a medical breakthrough the number of people...

  • Fast Track, 2001
    The Role of the Centromedian-Parafascicular Complex in the Origin and Pathophysiology of Parkinson's Disease

    This study will explore the role of the centromedian (CM)-carafascicular (Pf) thalamic complex in the pathophysiology of Parkinson's disease. We expect to confirm in an animal a common origin in the...

  • Fast Track, 2001
    A Zebrafish Assay for Parkinson's Disease Drugs

    We are developing an innovative model for Parkinson's disease using transgenic animals. The model is designed to rapidly screen thousands of potential small molecule drugs and to reduce the time it...

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