The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2019Diagnosing Early-Stage Parkinson’s Disease via a Urine Test for Extracellular Vesicles
Objective/Rationale:
There is a great need to develop new, readily accessible biomarkers — objective measures of disease — from biofluids (blood, urine, saliva or cerebrospinal fluid) for early... -
Research Grant, 2019Pharmacological Targeting of Inflammasome Activation Mechanisms in Synuclein Models of Parkinson's Disease
Promising Outcomes of Original Grant:
Our previous studies confirmed the activation of an immune system complex called the inflammasome is involved in chronic inflammation and the death of brain cells... -
Research Grant, 2019Antibodies Blocking Alpha-synuclein Toxicity and Spread for the Treatment of Parkinson’s Disease
Study Rationale:
Two main hallmarks of Parkinson’s disease (PD) are neurodegeneration and Lewy bodies, protein clumps comprising mainly of the protein alpha-synuclein. In diseases such as Parkinson’s... -
Research Grant, 2019Small Molecules That Promote Mitochondrial Movement as a Parkinson's Disease Therapy
Promising Outcomes of Original Grant:
Deficit in the movement of mitochondria -- powerhouses of the cell -- have been implicated in Parkinson's disease (PD) and other neurodegenerative diseases. We... -
Research Grant, 2019Deficit in Mitochondrial Transport as a Potential Measure of Parkinson's Disease
Study Rationale:
Dysfunction of mitochondria -- powerhouses of the cell -- is one of the possible causes of Parkinson's disease (PD). To supply all parts of the nerve cell with energy, mitochondria... -
Biomarkers of Protein Handling/Autophagy, Exosomes and Lipid, 2019Extracellular Vesicles Produced by Microglia as Novel Biomarkers of Parkinson's Disease
Study Rationale:
Extracellular vesicles (EVs) are small sacks that are released by all cells of the human body. They cross barriers within the body with relative ease and carry molecules that can be...
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Our funding programs support basic, translational and clinical research from academia and industry.