The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Fast Track, 2002Identification of Novel Dopamine Signaling Components Using C. Elegans Genetic Analysis
Neurons communicate with one another in the brain using the neurotransmitter dopamine and this communication is critical for normal brain function. In Parkinson's patients the neurons that make...
-
Fast Track, 2002Comparitive gene expression analysis of the brain in Parkinson's Disease and in familial encephalopathy with neuroserpin inclusion bodies (FENIB): implications for pathogenesis
Parkinson's disease (PD) is a common neurological disorder that affects the control of movement and frequently cognition. Examination of postmortem brain tissue from subjects with Parkinson's disease...
-
Fast Track, 2002Further evaluation fo the neuroprotective effects of citrus flavenoid tangeretin in a pre-clinical model of PD
Previously, Dr. Dexter's team has demonstrated that neurodegeneration in Parkinson's disease (PD) is associated with a process called oxidative stress. Oxidative stress is caused by either an increase...
-
Fast Track, 2002Dyskinesia & Abnormal Regulation of DARPP-32
L-DOPA-induced dyskinesia (abnormal involuntary movements, AIMs) is a major complication of the pharmacotherapy of Parkinson's disease. Subjects suffering from L-DOPA-induced dyskinesia show complex...
-
Fast Track, 2002Prevention and Treatment of Parkinson’s Disease Pathology in a-Synuclein Transgenic Mice
The hallmark lesions in the brains of patients with Parkinson's disease (termed Lewy bodies) are mainly composed of a-synuclein. This small protein normally regulates proper communication between...
-
Fast Track, 2002Dynamical interactions between basal ganglia structures and cerebral Cortex: an in Vivo Multi-site Recording Study
Recent successful strategies in treating Parkinson's disease consist of placing selective lesions in globus pallidus or stimulating in subthalamic nucleus (deep brain stimulation). Yet the dynamical...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.