The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Assessing the Effects of Parkin Activation in Pre-clinical Models
Study Rationale:
Protein parkin is involved in several subtypes of Parkinson's disease (PD). Loss of its activity leads to early-onset Parkinson's; therefore, increasing parkin activity may improve... -
Research Grant, 2018The Role of LRRK2 in Immune Response and Neurodegeneration Caused by Mitochondrial Dysfunction
Study Rationale:
Although mutations (changes) in the LRRK2 gene are more common than changes in other disease-linked genes in people with Parkinson's disease (PD), it remains unclear how the LRRK2 mut... -
Alpha-Synuclein Biology and Therapies, 2018Studying the Function of Modified Alpha-synuclein in Health and Disease
Study Rationale:
The exact cause of brain cell death in people with Parkinson's disease (PD) is not fully understood. Studies have revealed clumps of protein alpha-synuclein in brain cells. Modified... -
Research Grant, 2018Gait as a Measure of Parkinson's Disease
Study Rationale:
Gait impairment -- difficulty walking -- is arguably among the most disabling symptoms of Parkinson's disease (PD), as safe walking is critical for maintaining independence and... -
Research Grant, 2018Using Deep Learning to Evaluate Changes Associated with Parkinson’s Disease
Study Rationale:
Recent advances in artificial intelligence and, in particular, in one of its methods called deep learning offer exciting opportunities for the diagnosis and treatment of Parkinson’s... -
Research Grant, 2018Developing TLR2-Blocking Drugs to Reduce Alpha-synuclein-Induced Inflammation in Parkinson's Disease
Promising Outcomes of Original Grant: 100 words)
Synucleinopathies, including Parkinson's disease (PD), is a group of disorders affecting the central nervous system (CNS). These disorders share one key...
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Our funding programs support basic, translational and clinical research from academia and industry.