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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Access to Data and Biospecimens, 2017
    An 8-protein panel for diagnosis of Parkinson’s Disease: Sample request for replication in PDBP and PPMI

    Study Rationale: 

    We have previously found a panel of 8 proteins that can be measured in the blood that together distinguish people who have Parkinson’s Disease vs. people who do not.  We are trying to...

  • Research Grant, 2017
    Inflammatory Parkinson's Clinical Biomarker Profiling

    Study Rationale:
    This study aims to compare the immune system of Parkinson's disease (PD) patients and their caregivers in an effort to determine differences between these groups. Several recently...

  • LRRK2 Biology Consortium, 2017
    The Role of Variations in the LRRK2 Gene in Parkinson's Disease

    Study Rationale:
    Genes can influence one's chance of developing Parkinson's disease (PD), but it's not entirely clear how. In this study, we will use cells from people with Parkinson's to test how the...

  • Access to Data and Biospecimens, 2017
    LRRK2 in predicting Parkinson disease risk and progression in LRRK2 mutation carriers

    Study Rationale:       

    The G2019S mutation in the LRRK2 gene is responsible for thousands Parkinson disease (PD) cases. But, not all of the mutation carriers will develop PD. Currently, clinicians...

  • LRRK2 Biology Consortium, 2017
    Identification of Network, Activity and Behavioral Signatures of LRRK2 Expression

    Promising Outcomes of Original Grant:
    Our original project investigated how the LRRK2 mutation, the principal genetic cause of Parkinson's disease (PD), alters brain activity involved in movement...

  • Research Grant, 2016
    Investigation of the Role of PINK1-dependent Phosphorylation of Rab GTPases in Parkinson’s Disease

    Study Rationale:
    Mutations in the PINK1 gene lead to Parkinson’s disease. PINK1 belongs to a special class of enzymes known as protein kinases. We recently found that PINK1 targets a family of enzymes...

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