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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Target Validation, 2014
    Melanoma-related Gene as a Therapeutic Target for Parkinson's Disease

    Objective/Rationale:      
    Individuals with Parkinson’s disease (PD) are more likely to develop melanoma. Conversely, melanoma patients are at higher risk of developing PD. This bidirectional link...

  • Rapid Response Innovation Awards, 2014
    GSNOR Inhibition for Treatment of Parkinson’s Disease

    Study Rationale:                    
    Parkinson’s disease may be driven by inflammation and toxic, reactive products from oxygen metabolism. SAJE Pharma’s drugs target an enzyme called s...

  • Rapid Response Innovation Awards, 2014
    Drug Rescue of PINK1: New Therapeutic Modality for Treating Parkinson’s Disease

    Study Rationale:       
    Mitochondrial dysfunction has long been linked to Parkinson’s disease. We are investigating a class of drugs that increase the activity of an important mitochondrial quality...

  • Rapid Response Innovation Awards, 2014
    Functional Characterization of HIP1R in Parkinson’s Disease

    Study Rationale:                   
    Intracellular vesicle trafficking is an important mechanism for delivering proteins to their proper location where they can function within cells. Various genes...

  • Target Validation, 2014
    Transferrin Receptor 2 as a Target to Halt Iron Overload in Parkinson's Disease

    Objective/Rationale:             
    Iron is an element naturally present in the brain and is required for its proper function. Iron levels, however, must be tightly controlled because excessive amounts...

  • Research Grant, 2014
    Phase IIb Study of Intranasal Glutathione in Parkinson’s Disease

    Study Rationale:                   
    The loss of the antioxidant glutathione in the brain of individuals with Parkinson’s disease (PD) occurs years before the onset of motor symptoms. Glutathione has...

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