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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Biomarker Development, 2012
    VILIP-1 as Diagnostic and Prognostic Biomarker for Parkinson's Disease

    Objective/Rationale:             
    Novel biomarkers are key for successful clinical development of Parkinson’s therapies. In Alzheimer’s disease the calcium sensing protein VILIP-1 (visinin-like...

  • Therapeutics Development Initiative, 2012
    Potential of Novel Insulin Sensitizers to Treat Dyskinesia

    Objective/Rationale:             
    The goal of this project is to determine whether the mTOT insulin sensitizer, MSDC-0160, can both prevent (when given at the same time) or reverse (when given later)...

  • MJFF Research Grant, 2012
    Non-kinase Targets in LRRK2 Biology

    Objective/Rationale:             
    We aim to understand how mutations in one gene, LRRK2, lead to Parkinson’s disease. We will do this by focusing on one region of the protein that has not had much...

  • Rapid Response Innovation Awards, 2012
    Modulation of the CD40/CD40-Ligand Neuroinflammation Pathway in Parkinson's Pre-Clinical Models

    Objective/Rationale:             
    In PD and PD-related models, neuroinflammation has been well documented. However, it is still unknown if neuroinflammation is a cause, contributor, or bystander in PD...

  • Resource: Utilizing Samples from the Arizona Parkinson’s Di, 2012
    Preferential Loss of Serotonin Axon Subtypes in Depression in Parkinson's Disease

    Objective/Rationale:
    Depression occurs in Parkinson’s disease (PD) much more frequently than in the general population, and is a major factor contributing to decreased quality of life for affected...

  • MJFF Research Grant, 2012
    Network Biomarkers for the Assessment of Parkinson's Disease: A Multi-modal Optimization Study

    Objective/Rationale:
    This study will compare positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) for measuring the activity of Parkinson's disease-specific brain...

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Our funding programs support basic, translational and clinical research from academia and industry.

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