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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2010
    Viral Over-expression of Alpha Synuclein

    Promising Outcomes of Original Grant:
    In our previous grant, we attempted to create a bilateral model of PD using viral over expression of alpha-synuclein. The performance of the study was near...

  • MJFF Research Grant, 2010
    A Rodent Model of Pathological Gambling Associated with Medicated Parkinsonian Patients

    Promising Outcomes of Original Grant:
    In keeping with our original hypothesis, we determined the following:  1) Being in a parkinsonian state (i.e., following 6-OHDA-induced lesions) alters impulsivity...

  • Improving Delivery of Parkinson's Disease Therapeutics to th, 2010
    Novel Antibodies for the Delivery of Parkinson's Therapeutics

    Promising Outcomes of Original Grant:
    The initial granting period resulted in the successful identification of antibodies capable of targeting and internalizing into novel in vitro blood-brain barrier...

  • Target Validation, 2010
    Validation of VPS41, a Protein Involved in Lysosomal Trafficking, as a Target for Parkinson Disease Therapy

    Promising Outcomes of Original Grant:
    VPS41 was identified in a C. elegans system. In the original funded grant, we demonstrated that human VPS41 (hVPS41) was also protective in C. elegans, performed a...

  • MJFF Research Grant, 2010
    Promoting Widespread Data Sharing Among Scientists

    Objective/Rationale
    When scientists carry out experiments and observations, they typically have very specific questions.  It is frequently the case that data collection is relevant to issues and...

  • Target Validation, 2010
    Pharmacodynamics and Neuroprotective Effects of Pegylated G-CSF

    Promising Outcomes of Original Grant:
    We have discovered that a specific protein, granulocyte-colony stimulating factor (G-CSF), is effective in reducing nerve cell death and thereby disease...

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Our funding programs support basic, translational and clinical research from academia and industry.

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