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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • The Role of Inflammation in Parkinson's Disease, 2003
    The Role of TNF-Mediated Dopaminergic Neurotoxicity in Parkinson's Disease: Novel Anti-TNF Biologics as Biochemical Tools and New Therapeutic Agents

    Loss of dopamine-producing neurons is a hallmark of Parkinson's disease and inflammation-driven oxidative stress is believed to play a significant role in this neurodegenerative process.

    Strong...

  • Community Fast Track, 2003
    Osteopontin as a regulator of the inflammatory response to nigral celldegeneration

    The cause of nerve cell death in the substantia nigra in Parkinson's disease remains unknown. However, one feature of the degenerative process is the onset of inflammation in this brain region due to...

  • Community Fast Track, 2003
    Role of Delta FosB in the Development of Levodopa-induced Dyskinesia

    The goal of this project is to study mechanisms responsible for the dyskinesia side effect of levodopa seen in patients with Parkinson's disease. The proposed experiments focus on a protein, called...

  • Community Fast Track, 2003
    NBD Peptides in MPTP Pre-clinical Model

    Understanding the mechanism of the disease process of Parkinson's dis and development of effective neuroprotective therapeutic approach to halt the disease progression are of paramount importance. It...

  • Community Fast Track, 2003
    Biomarker Discovery in Parkinson’s Disease

    The primary goal of our studies is to expand our ongoing biomarker discovery program in order to establish biological markers of Parkinson's disease (PD). The imperative to develop effective therapies...

  • Community Fast Track, 2003
    Mitochondrial Trafficking in Dopaminergic Neuron Injury

    Mitochondria are considered to be the "power house" of all cells, including neurons, because they convert food into energy in the form that cells can use. When mitochondria fail, cells typically die...

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