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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • The Role of Inflammation in Parkinson's Disease, 2003
    The Role of Subclinical Rejection in Graft-mediated Dyskinesias

    The results of two recent Parkinson's disease (PD) clinical trials designed to replace cells lost to the disease have documented that replacing these cells can have negative side effects. In...

  • The Role of Inflammation in Parkinson's Disease, 2003
    Studies on the effects of peripheral inflammation on the progression of Parkinson ´s disease

    Inflammation is the first line of defense of the organism after an insult is detected. Although usually beneficial, it could be detrimental if its magnitude or duration is not adequate. In the brain...

  • The Role of Inflammation in Parkinson's Disease, 2003
    Involvement of CD200/CD200 Receptor Interactions in Inflammatory-mediated Pathology in PD

    Inflammation has been shown in many diseases to be a destructive process when occurring under inappropriate circumstances. Based on a wide range of studies, it appears that dopaminergic neurons in the...

  • The Role of Inflammation in Parkinson's Disease, 2003
    Activation of neuroinflammatory glial response by neuromelanin, its role in neurodegeneration, and therapeutic strategies for Parkinson's disease

    In Parkinson's disease a preferential loss of neurons containing neuromelanin occurs with respect to the neurons which do not contain neuromelanin. We have previously shown that neuromelanin inside...

  • Molecular Mechanisms of Dyskinesia in Parkinson's Disease, 2003
    Mechanisms of Graft-Induced Dyskinesias in an Animal Model of Parkinson's Disease

    Embryonic dopamine neurons can be transplanted to the region of the brain that becomes depleted of dopamine in Parkinson's disease (PD). Studies performed in both patients and animal models of PD have...

  • Community Fast Track, 2003
    Regulation of Dopaminergic Pathways by Eph Family Receptors

    Replacing dopaminergic neurons is an attractive alternative in the treatment of Parkinson's disease (PD). However, a successful treatment relies not only on the introduction of new neurons, but also...

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