The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Measuring Alpha-Synuclein in Extracellular Vesicles, 2024Development of an Alpha-synuclein Blood Biomarker for Clinical Use
Study Rationale: In Parkinson’s disease (PD), alpha-synuclein forms abnormal clumps in nerve cells, causing their death. By the time people develop PD, these alpha-synuclein aggregates have spread...
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Research Grant, 2024Qualitative Evaluation of Draft Questionnaires for Patient-reported Outcome Measures of Non-motor Symptoms in Early-stage Parkinson's Disease
Study Rationale: This project seeks to address an unmet need for fit-for-purpose, clinical outcome assessments for early-stage Parkinson’s disease (PD) to be used in clinical trials to capture the...
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2021 RFA: PIPETTE 4R Tau and Alpha-Synuclein PET Tracer Development, 2024SUPPLEMENT: Rescreening of the MJFF Compound Library to Identify Molecules that Can be Used to Monitor Alpha-synuclein
Study Rationale: Alpha-synuclein is a key protein involved in the pathology of Parkinson’s disease (PD). We recently confirmed that two compounds developed under the MJFF Alpha-synuclein Imaging...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2024Strengthening Evidence-based Regulatory Decision-making to Address the Impact of Pesticides on Parkinson's Disease Risk
Study Rationale: Parkinson's disease (PD) is a growing global health concern, and recent research suggests that exposure to certain toxic chemicals, such as pesticides, may contribute to its...
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Freezing of Gait, 2024Adaptive Cortical Neuromodulation Using a Brain-machine Interface to Treat Freezing of Gait in Parkinson’s Disease
Study Rationale: Difficulties with walking can have significant impacts on the quality of life of people with Parkinson’s (PwP). One of the most serious is freezing of gait (FOG), which are brief but...
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Research Grant, 2024Validation of Functional Staging of Parkinson’s Disease Using the Critical Path for Parkinson’s (CPP) Integrated Parkinson’s Database
Study Rationale: Researchers recently proposed defining Parkinson’s disease (PD) based on a test for abnormal alpha-synuclein in spinal fluid and adopting a staging system based on measures (or scales...
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Our funding programs support basic, translational and clinical research from academia and industry.