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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2020
    GBA Variations, Cholinergic Degeneration, and Cognitive Decline in Parkinson’s Disease

    Study Rationale:
    Mutations in the GBA gene are the most common genetic risk factors for Parkinson’s disease. People with GBA mutations (GBA-PD) may develop the disease at a younger age and may have...

  • Research Grant, 2011
    Comparing Cognitive Scales in the MUSTARDD-PD Study

    Objective/Rationale:
    Some people with Parkinson’s may develop dementia during their disease course. Being able to detect problems with mental function at an early stage, to monitor and to reliably...

  • Research Grant, 2013
    Validation of the Movement Disorders Society Criteria for Mild Cognitive Impairment in Parkinson’s Disease

    Objective/Rationale:          
    Dementia in Parkinson’s disease (PD) is a serious health issue and a major concern for many PD patients. Mild cognitive impairment (MCI) is considered a transitional...

  • Developing and Validating Web-Based Clinical Assessments for, 2008
    Online Motor and Cognitive Analysis System

    Objective/Rationale:
    Despite advances in treatment approaches to Parkinson’s disease over the past 20 years, patient assessment methods have advanced little during this same period. Therefore, a...

  • Research Grant, 2012
    Phase I-B Clinical Trial of AVE8112 for Cognitive Impairment in Parkinson’s Disease

    Objective/Rationale:
    Cognitive impairment is a symptom seen in Parkinson’s disease (PD) patients, and some can progress to dementia. AVE8112 is a PDE4 inhibitor that was in development by the...

  • Improved Biomarkers and Clinical Outcome Measures, 2015
    Validation of a Performance-based Assessment of Functional Ability Related to Cognition in Parkinson’s Disease

    Study Rationale:                   
    There is a pressing need for new treatments to address cognitive impairment in Parkinson’s disease, yet there is no consensus on how to best evaluate their...

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