The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Cognitive Deficits and Mood Disorders in Parkinson's Disease, 2008Validating the Montreal Cognitive Assessment for the Diagnosis of Mild Cognitive Impairment in Parkinson's Disease
Objective/Rationale:
Dementia affects up to 80 percent of Parkinson’s disease patients, and the prevalence of other dementias including Alzheimer’s disease is high in this age group. A need exists for... -
Cognitive Deficits and Mood Disorders in Parkinson's Disease, 2008A Rodent Model of Pathological Gambling Associated with Medicated Parkinsonian Patients
Objective/Rationale:
The increase in impulsive and risky behaviors, like gambling, hyper-sexuality, and compulsive shopping are emotionally and financially devastating, and impose a significant burden... -
Cognitive Deficits and Mood Disorders in Parkinson's Disease, 2008Cognitive Decline in Parkinson's Disease
Objective/Rationale:
There are many studies on cognitive and behavioral alterations in Parkinson’s disease, but each of these investigations brought only a small piece of a large puzzle. Consequently... -
Program-non-specific Funding, 2008Validation of TorsinA as a Target for PD Therapy in Mammalian Models
Objective/Rationale:
Mutations in the protein torsinA cause a hereditary form of dystonia. While the normal function of torsinA is not entirely clear, it is thought to be a “chaperone,” a molecule... -
Rapid Response Innovation Awards, 2008Exploring a Novel Pathogenetic Mechanism in Parkinson's Disease
Objective/Rationale:
We recently reported that neuropathological changes gradually propagate from Parkinson disease patients’ brains to grafted neurons. Over one decade after graft surgery, we found... -
Rapid Response Innovation Awards, 2008Expression, Purification and Crystallization of the LRRK2 Kinase
Objective/Rationale:
Mutations in the gene encoding Leucine Rich Repeat Kinase 2 (LRRK2) are found in a substantial number of patients with familial or sporadic forms of Parkinson’s disease, and it has...
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Our funding programs support basic, translational and clinical research from academia and industry.