The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2008Generating Patient-Specific Induced Pluripotent Stem Cells to Study Parkinson's Disease
Objective/Rationale:
One of the major hurdles for Parkinson’s research is the lack of live dopamine neurons from patients for long-term studies and drug screens. This project will use the newly... -
Rapid Response Innovation Awards, 2008Posiphen as a Well-tolerated Alpha-synuclein Inhibitor and a Potential 5'UTR Directed Drug Treatment of Parkinson's Disease
Objective/Rationale:
An inter-relationship exists between the Parkinson’s disease-related protein alpha-synuclein and the Alzheimer’s Aß-amyloid plaque protein. Phenserine reached clinical assessment... -
Rapid Response Innovation Awards, 2008The Role of the Unfolded Protein Response (UPR) in Parkinson's Disease
Objective/Rationale:
Our general objective is to investigate the role of the cellular stress responses linked to organelle damage such as the Unfolded Protein Response in the development of Parkinson... -
Rapid Response Innovation Awards, 2008A Novel Cell Model for LRRK2 Parkinson's Disease
Objective/Rationale:
The aim of this project is to create a model of Parkinson’s disease using skin cells from patients who have an inherited form of Parkinson’s disease. Using newly developed stem... -
Rapid Response Innovation Awards, 2008Identification of binding proteins for alpha-synuclein oligomers in brain and cells
Mutations in the PARK-1 and PARK-4 genes leads to alpha-synuclein aggregation with pathology eventually resembling that of sporadic PD. One question is whether the insoluble form of alpha-synuclein is...
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Rapid Response Innovation Awards, 2008The Glucosylceramide Pathway in Parkinson's Disease and other Synucleinopathies: Genetic defects, Neuropathological characterization and cell culture models
Objective/Rationale:
Mutations in the beta glucocerebrosidase (GBA) gene are associated with Parkinson’s disease. Only a small number of neuropathologically confirmed PD, multiple system atrophy (MSA)...
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Our funding programs support basic, translational and clinical research from academia and industry.