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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2022
    Use of Itaconate to Improve Metabolic Regulation in Parkinson's Disease

    Study Rationale: In people with Parkinson’s disease (PD), chronic inflammation and metabolic reprogramming triggers neuronal cell death. Impaired function of the proteins involved in cellular...

  • Research Grant, 2022
    Using a Systems-based Approach to Study the Molecular Processes Underlying Parkinson’s Disease: The Foundational Data Initiative

    Study Rationale: This effort aims to produce foundational data that will provide immediate insight and a resource for understanding the molecular basis of Parkinson disease (PD). The work, conducted...

  • [RFA] Use of PD Biosamples - Spring 2020, 2022
    Studying DNA Methylation in Parkinson’s Disease Using the Systemic Synuclein Sampling Study

    Study Rationale: Developing accurate and reliable biomarkers for Parkinson’s disease (PD) is critical for detecting early changes with the hope of better understanding the mechanisms of disease and...

  • Diversity, Equity and Inclusivity in Parkinson's research, 2022
    Multiculturalism, Reported Cognitive Complaints and Predictors of Cognitive Decline Following Deep Brain Stimulation

    Study Rationale: Cognitive decline is common in people with Parkinson’s disease (PD), and changes in thinking and performance on objective cognitive tests reported by individuals and their family are...

  • Alpha-synuclein Seed Amplification Assay Program, 2022
    Comparison and Cross-Validation of Alpha-synuclein Seed Aggregation Assays in Samples of Skin, Cerebrospinal Fluid, Saliva and Tears

    Study Rationale: Identification of misfolded alpha-synuclein aggregates in postmortem brain samples remains a major histopathological hallmark for confirming the diagnosis of Parkinson’s disease (PD)...

  • Diversity, Equity and Inclusivity in Parkinson's research, 2022
    Studying Parkinson’s Disease Clinical Features, Progression and Quality of Care in Latino Patients from a Population-based Epidemiological Study in the United States

    Study Rationale: Social and medical factors can affect the rates of Parkinson’s disease (PD) and how the disorder manifests in different individuals. These factors may carry different weight in...

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