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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • , 2022
    The Heads-Up Trial: Exploring the Effects of Sleeping in a Head-up Tilt Position on Blood Pressure in Parkinson’s Disease

    Study Rationale: Parkinson’s disease (PD) affects the function of the autonomic nervous system, which controls blood pressure (BP), often resulting in both a low BP upon rising (orthostatic...

  • Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2022
    Development of Immune-based Biomarkers for Parkinson’s Disease

    Study Rationale: Preclinical and human studies have demonstrated the potential of using granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment of Parkinson’s disease (PD). GM-CSF...

  • Diversity, Equity and Inclusivity in Parkinson's research, 2022
    Promoting Diversity, Equity and Inclusion in Parkinson’s Disease (PD) Research: Clinical Disease Course and Healthcare Access in Black People with PD

    Study Rationale: Few studies have been conducted on the clinical disease course and healthcare access in Black people with Parkinson’s disease (PD) compared to their White counterparts, and the...

  • Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2022
    Identification and Characterization of Compounds that Regulate the Activity of the LRRK2 System

    Study Rationale: Genetic mutations that lead to the activation of the enzyme LRRK2 are a major cause of inherited Parkinson's disease (PD). We have identified a protein, termed PPM1H, that counteracts...

  • , 2022
    Fostering Inclusivity in Research Engagement for Underrepresented Populations in Parkinson’s Disease, Phase II (FIRE-UP PD II)

    Study Rationale: In recent years, scientists have learned that improving representation of all people in clinical research is an important way to fully understand diseases. This also ensures that new...

  • Alpha-synuclein Seed Amplification Assay Program, 2022
    Quantifying Alpha-synuclein Aggregates Using Nanopore Sensor

    Study Rationale: Parkinson’s disease (PD) is associated with an accumulation of alpha-synuclein aggregates in the brain; however, the current methods used to identify these aggregates in biological...

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